Avanafil metabolite M4 |
| カタログ番号GC42879 |
アバナフィル代謝物M4は、リン酸ジエステラーゼ5（PDE5）阻害剤であるアバナフィルの主要な活性代謝物です。
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Sample solution is provided at 25 µL, 10mM.
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Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanafil metabolite M4 and avanafil metabolite M16 , as well as minor metabolites. Avanafil metabolite M4 inhibits PDE5 with 18% of the potency of avanafil.
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