ML-9 |
カタログ番号GC49440 |
ML-9 は Akt キナーゼの選択的かつ強力な阻害剤であり、ミオシン軽鎖キナーゼ (MLCK) および間質相互作用分子 1 (STIM1) 活性を阻害します。 ML-9 は MLCK、PKA、PKC の活性をそれぞれ 4、32、54 μM の Ki 値で阻害します。 ML-9 は、オートファゴソームの形成を刺激し、その分解を阻害することにより、オートファジーを誘導します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 105637-50-1
Sample solution is provided at 25 µL, 10mM.
ML-
1.Ito, S., Kume, H., Honjo, H., et al.ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealisEuropean Journal of Pharmacology486325-333(2004) 2.Smith, U., Carvalho, E., Mosialou, E., et al.PKB inhibition prevents the stimulatory effect of insulin on glucose transport and protein translocation but not the antilipolytic effect in rat adipocytesBiochemical and Biophysical Research Communications268315-320(2000)
Average Rating: 5
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