12(S)-HETE-19,20-alkyne (Synonyms: Click Tag 12(S)-HETE-19,20-alkyne, Click Tag 12(S)-Hydroxyeicosatetraenoic Acid-19,20-alkyne) |
カタログ番号GC40349 |
12(S)-HETEは哺乳動物の血小板におけるリポキシゲナーゼ生成物の主要なものです。
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Sample solution is provided at 25 µL, 10mM.
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM. 12(S)-HETE-19,20-alkyne is a form of 12(S)-HETE with an ω-terminal alkyne. The terminal alkyne group can be used in click chemistry linking reactions, to tag 12(S)-HETE with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.
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