Fmoc-NH-PEG4-CH2CH2COOH |
カタログ番号GC60852 |
Fmoc-NH-PEG4-CH2CH2COOH は、抗体薬物複合体 (ADC) の合成に使用される切断可能な ADC リンカーです。 Fmoc-NH-PEG4-CH2CH2COOH は、PROTAC の合成に使用できる PEG ベースの PROTAC リンカーでもあります。
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Cas No.: 557756-85-1
Sample solution is provided at 25 µL, 10mM.
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14.
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