c-met-IN-1 |
| カタログ番号GC35717 |
c-met-IN-1 (化合物 16) は、強力かつ選択的な c-Met 阻害剤であり、IC50 は 1.1 nM で、抗腫瘍活性があります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2084836-84-8
Sample solution is provided at 25 µL, 10mM.
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c-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity.[1]. IC50: 1.1 nM (c-Met)[1]
c-met-IN-1 (compound 16) exhibits high selectivity and remarkable cytotoxicity against HT-29, MKN-45 and A549 cells with IC50 values of 0.08 μM, 0.22 μM and 0.07 μM, respectively[1].
[1]. Wang X, et al. Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors. Bioorg Med Chem. 2017 Feb 1;25(3):886-896.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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