Oxybutynin chloride (Synonyms: MJ4309-1) |
| カタログ番号GC14703 |
オキシブチニンクロリドは、マウスの膀胱および大脳皮質における特異的 [3H]NMS 結合に対する Kis がそれぞれ 14.3 および 5.55 nM の経口活性型および競合的 mAChR アンタゴニストです。
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Cas No.: 1508-65-2
Sample solution is provided at 25 µL, 10mM.
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Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1].
References:
[1]. Li H, The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036.
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