Prostaglandin J2 (Synonyms: PGJ2) |
| カタログ番号GC18653 |
プロスタグランジンJ2（PGJ2）は、アルブミンの存在によって加速されるC-9水酸基の除去によってPGD2から形成されます。
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Cas No.: 60203-57-8
Sample solution is provided at 25 µL, 10mM.
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Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ2 inhibits platelet aggregation with an IC50 of about 5-10 nM. PGJ2 has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines. However, this activity has been attributed to further metabolites of PGJ2 and not the parent compound itself.
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