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Prostaglandin J2

Catalog No.: GC18653

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin.

Prostaglandin J2 Chemical Structure

Size Price Stock Qty
500μg
$117.00
In stock
1mg
$219.00
In stock
5mg
$920.00
In stock
10mg
$1,608.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ2 inhibits platelet aggregation with an IC50 of about 5-10 nM. PGJ2 has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines. However, this activity has been attributed to further metabolites of PGJ2 and not the parent compound itself.

Chemical Properties

Cas No. 60203-57-8 SDF
Chemical Name 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid
Canonical SMILES CCCCC[C@H](O)/C=C/[C@H]([C@@H](C/C=C\CCCC(O)=O)C=C1)C1=O
Formula C20H30O4 M.Wt 334.5
Solubility DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2),PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-.DEL Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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