Target Protein-binding moiety 4 (Synonyms: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2) |
| カタログ番号GC32863 |
標的タンパク質結合部分 4 (Molibresib カルボン酸) は、BET を標的とする PROTAC の結合反応用の I-BET762 ベースの弾頭リガンドです。標的タンパク質結合部分 4 (モリブレシブカルボン酸) は、pIC50 が 5.1 の BRD4 阻害剤です。
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Cas No.: 1300019-38-8
Sample solution is provided at 25 µL, 10mM.
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Target Protein-binding moiety 4 is a BRD4(1) inhibitor with an IC50 of 7.9 μM.
Target Protein-binding moiety 4 (compound 32) is a BRD4 (1) inhibitor with an IC50 of 7.9 μM[1].
[1]. Yifei Yang, et al. Combined pharmacophore models as virtual screening protocol against BRD4(1) inhibitor. Medicinal Chemistry Research (2016), 25(4), 585-595.
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