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AA 147

Catalog No.GC50566

AA 147은 소포체(ER) 단백성 조절제입니다.

Products are for research use only. Not for human use. We do not sell to patients.

AA 147 Chemical Structure

Cas No.: 393121-74-9

Size 가격 재고 수량
5 mg
US$66.00
재고 있음
25 mg
US$236.00
재고 있음

Tel:(909) 407-4943 Email: sales@glpbio.com

고객 리뷰

Based on customer reviews.

  • GlpBio Citations

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM).

Plate et al (2016) Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. Elife 5 e15550 PMID:27435961

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 2 reference(s) in Google Scholar.)

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