PGP-4008 |
| Catalog No.GC44615 |
PGP-4008은 특정 P-당단백질(Pgp) 억제제입니다. PGP-4008은 독소루비신과 함께 제공될 때 쥐 동계 Pgp 매개 다중 약물 내성(MDR) 고형 종양 모델에서 종양 성장을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 365565-02-2
Sample solution is provided at 25 µL, 10mM.
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PGP-4008 is a selective inhibitor of P-glycoprotein (P-gp) that does not affect the activity of multidrug resistance-related protein 1 (MRP1). It is effective in vitro and, when delivered intraperitoneally, in vivo, inhibiting tumor growth when given with doxorubicin . PGP-4008 also enhances the ability of docetaxel to inhibit growth and drive apoptosis in ovarian cancer cells.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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