PNU112455A hydrochloride |
| Catalog No.GC39421 |
PNU112455A 염산염은 ATP-경쟁적 CDK2 및 CDK5 억제제입니다. PNU112455A 염산염은 각각 3.6 및 3.2μM의 Kms로 CDK2 및 CDK5의 ATP 부위에 결합합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 21886-12-4
Sample solution is provided at 25 µL, 10mM.
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PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively[1].
[1]. Clare PM, et al. The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. J Biol Chem. 2001 Dec 21;276(51):48292-9.
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