Cardiovascular
Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Targets for Cardiovascular
Products for Cardiovascular
- Cat.No. 상품명 정보
- GC52065 4-Methoxyphenyl-β-D-Glucopyranoside An aryl glycoside with ice recrystallization inhibitory activity
- GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation
- GC40782 5(Z),11(Z),14(Z)-Eicosatrienoic Acid 5(Z),11(Z),14(Z)-Eicosatrienoic acid is a polyunsaturated fatty acid found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods.
- GC42498 5-chloro Hydrochlorothiazide 5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.
- GC45357 5-Chlorouracil
- GC40336 5-cis Carbaprostacyclin 5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin.
- GC41483 5-hydroxy Propranolol 5-hydroxy Propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist.
- GC42563 5-methyl-2-HOBA (hydrochloride) 5-methyl-2-HOBA is an isoketal scavenger.
- GC46706 5-Methyltetrahydrofolic Acid (hydrate) A biologically active form of folic acid
- GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1.
- GC40585 6α-Prostaglandin I1 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.
- GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone
- GC40586 6β-Prostaglandin I1 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions.
- GC40535 6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2.
- GC18219 6-hydroxy Warfarin 6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .
- GC18820 6-keto Prostaglandin E1 6-keto PGE1 is a metabolite isolated after the incubation of PGI2 with rabbit liver microsomes.
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GC40202
7α-hydroxy Cholesterol-d7
7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.
- GC40201 7β-hydroxy Cholesterol-d7 7β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7β-hydroxy cholesterol by GC- or LC-MS.
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GC46241
7-keto Cholesterol-d7
7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL
- GC18737 8-iso Prostaglandin E1 Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin.
- GC42634 9(R)-HODE cholesteryl ester 9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.
- GC42635 9(S)-HODE cholesteryl ester 9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions.
- GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2.
- GA20031 A 71915 A 71915는 매우 강력하고 경쟁력 있는 나트륨 이뇨 펩티드 수용체 A(ANP, NPRA) 길항제입니다(pKi= 9.18).
- GC48486 AAA A GPR75 antagonist
- GC49576 Abnormal Cannabidiol-d3 Internal standard for the quantification of abnormal cannabidiol
- GP10121 Ac-Endothelin-1 (16-21), human
- GC52058 Acebutolol 아세부톨롤은 경구 활성 β1 아드레날린 수용체(β1AR) 길항제입니다.
- GC42690 Acecainide (hydrochloride) Acecainide is an active metabolite of the class III antiarrhythmic procainamide.
- GC49614 Acenocoumarol-d4 Acenocoumarol-d4는 Acenocoumarol로 표시된 중수소입니다.
- GC46782 Acetochlor An herbicide
- GP10059 Acetyl Angiotensinogen (1-14), porcine
- GC18474 Acetyldigitoxin Acetyldigitoxin(Digitoxin 3'''-Acetate)은 심장 배당체입니다.
- GC49406 ACT-373898 ACT-373898은 Macitentan의 비활성 카르복실산 대사 산물입니다.
- GC46805 Adefovir-d4 An internal standard for the quantification of adefovir
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GP10113
Adrenomedullin (1-12), human
An N-terminal fragment of adrenomedullin
- GC42738 Adrenomedullin (13-52) (human) (trifluoroacetate salt) Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52).
- GC42746 AFP 07 (free acid) Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.
- GC46820 AHU377-d4 AHU377-d4(AHU-377-d4)는 Sacubitril로 표시된 중수소입니다.
- GC49110 AICA Ribonucleotide An AMPK activator
- GC46821 Ajoene 마늘에서 추출한 화합물인 아조엔은 항혈전 및 항진균제입니다.
- GC52023 Alfuzosin-d7 An internal standard for the quantification of alfuzosin
- GC46835 Alyssin 십자화과 야채에서 발견되는 Alyssin은 세포 내 활성 산소 종과 tubulin depolymerization을 증가시켜 HepG2에서 항암 활성을 나타냅니다.
- GC49262 Alytesin (trifluoroacetate salt) A neuropeptide with diverse biological activities
- GC42778 Amauromine Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 μM.
- GC49638 Ambrisentan-d3 An internal standard for the quantification of ambrisentan
- GC46842 Amiodarone-d4 (hydrochloride) Amiodarone-d4(염산염)는 Amiodarone 염산염의 표지된 중수소입니다.
- GC46845 Amlodipine-d4 (maleate) An internal standard for the quantification of amlodipine
- GP10099 amyloid A protein fragment [Homo sapiens] Apolipoproteins related to HDL in plasma
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GP10077
Angiotensin (1-7)
Ang-(1-7) (H - Asp - Arg - Val - Tyr - Ile - His - Pro - OH)는 내인성 펩타이드 단편으로, Ang I 또는 Ang II를 각각 endo- 또는 carboxy-peptidase를 통해 생산할 수 있습니다[1].
- GP10074 Angiotensin 1/2 (1-5)
- GP10067 Angiotensin 1/2 (1-6)
- GP10144 Angiotensin 1/2 (1-7) amide
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GP10012
Angiotensin 1/2 (1-8) amide
Vasoconstrictor
- GP10025 Angiotensin 1/2 (1-9)
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GP10045
Angiotensin 1/2 (2-7)
Vasoconstrictor
- GP10079 Angiotensin 1/2 (5-7)
- GP10120 Angiotensin 1/2 + A (2 - 8) Vasoconstrictor
- GC52415 Angiotensin A (trifluoroacetate salt) An AT1 and AT2 receptor agonist and active metabolite of angiotensin II
- GP10087 Angiotensin I (human, mouse, rat)
- GC42808 Angiotensin I (human, rat, mouse) (trifluoroacetate salt) Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II by angiotensin-converting enzyme (ACE).
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GP10023
Angiotensin II
AT1 및 AT2 수용체에서의 작용제
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GC42809
Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)
Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II.
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GC46856
Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)
An endogenous angiotensin II fragment
- GP10110 Angiotensin III (human, mouse) An agonist at AT1 and AT2 receptors
- GP10137 ANP (1-11), rat
- GC42821 AP219 AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria.
- GC52427 Apelin-12 (human, mouse, rat, bovine) (acetate) An endogenous agonist of the APJ receptor
- GC49314 Arecaidine propargyl ester (hydrobromide) A muscarinic M2 agonist
- GC46879 Argatroban-d3 (hydrochloride) An internal standard for the quantification of argatroban
- GC48997 Argipressin (acetate) A peptide hormone with vasoconstrictive and antidiuretic activities
- GC40848 Aspalatone Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism.
- GC39554 AT2 receptor agonist C21 AT2 수용체 작용제 C21은 AT2 수용체 및 AT1 수용체에 대해 각각 0.4 nM 및 >10 μM의 Ki 값을 갖는 약물 유사 선택적 안지오텐신 II AT2 수용체 작용제이다.
- GC46889 Atorvastatin (calcium salt hydrate) An HMG-CoA reductase inhibitor
- GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone
- GC46890 Atorvastatin-d5 (calcium salt) An internal standard for the quantification of atorvastatin
- GC42869 Atpenin A5 Atpenin A5는 강력하고 고도로 특이적인 complex II 억제제(IC50 ~10 nM)이며 효과적인 mKATP 채널 작용제이자 심장 보호제입니다.
- GP10061 Atrial Natriuretic Factor (1-29), chicken Atrial Natriuretic Factor (1-29), chicken, (C130H223N51O41S5), a peptide with the sequence H2N-SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH, MW= 3316.8.
- GC52359 ATX-100 An ionizable cationic lipid
- GC49784 AZD 2716 An sPLA2 inhibitor
- GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ.
- GC49057 Azelastine-13C-d3 (hydrochloride) An internal standard for the quantification of azelastine
- GC18313 BAR501 Impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1).
- GC48589 Bassianin A fungal metabolite
- GC46911 Beauveriolide I Beauveriolide I은 곤충병원성 진균 Beauveria sp.의 대사산물입니다.
- GC46912 Beauveriolide III Beauveriolide III는 마우스 대식세포에서 지질 방울 형성의 억제제입니다.
- GC46913 Benazepril-d5 (hydrochloride) An internal standard for the quantification of benazapril
- GC42913 Benazeprilat Benazeprilat은 경구 활성 및 항고혈압 활성을 갖는 카르복실 함유 ACE 억제제인 benazepril의 활성 대사산물입니다.
- GC49836 Benoxaprofen 베녹사프로펜(LRCL 3794)은 강력하고 오래 지속되는 항염증 및 해열 화합물입니다.
- GC49403 Benzarone Benzarone(Fragivix)은 난모세포에서 IC50이 2.8μM인 강력한 인간 요산 수송체 1(hURAT1) 억제제입니다.
- GC42924 Beraprost (sodium salt) Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function.
- GC49387 Berberine-d6 (chloride) An internal standard for the quantification of berberine
- GC42941 Bis(methylthio)gliotoxin 비스(메틸티오)글리오톡신은 글리오톡신보다 침습성 아스페르길루스증에 대한 더 안정적이고 신뢰할 수 있는 마커이며 진단에 사용하기에 적합합니다.
- GC18716 Bisindolylmaleimide XI (hydrochloride) Bisindolylmaleimide XI(염산염)(Ro 32-0432)는 PKCα, PKCIIII, PKCβ, PKCIII에 대해 9 nM, 28 nM, 31 nM, 37 nM 및 108 nM의 IC50을 갖는 강력하고 선택적이고 경구 활성인 PKC 억제제입니다. , 각각.
- GP10071 BNP (1-32), human
- GA20982 Boc-D-Phe-Pro-OH A synthetic intermediate
- GC42966 Bopindolol (malonate) Bopindolol((±)-Bopindolol) malonate는 β의 경구 활성 길항제입니다.
- GC48620 BPKDi BPKDi는 PKD1, PKD2 및 PKD3에 대해 각각 1nM, 9nM 및 1nM의 IC50을 갖는 강력한 비피리딜 PKD 억제제입니다.
- GC49885 BQ-3020 (trifluoroacetate salt) A peptide ETB receptor antagonist