>>Signaling Pathways>> Cell Cycle/Checkpoint>> G-quadruplex>>TMPyP4 tosylate

TMPyP4 tosylate (Synonyms: TMP-1363, TMPyP4 4-methylbenzenesulfonate)

Catalog No.GC12092

TMPyP4 토실레이트(TMP 1363)는 G-사중체와 IGF-1 사이의 상호작용을 억제하는 사중체 특이적 리간드입니다. TMPyP4 토실레이트(TMP 1363)는 골육종 세포주에서 항종양 효과가 있는 텔로머라제 억제제입니다.

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TMPyP4 tosylate Chemical Structure

Cas No.: 36951-72-1

Size 가격 재고 수량
10mM (in 1mL Water)
US$34.00
재고 있음
50mg
US$78.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1[1]. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines[2].

References:
[1]. Chen H, et al. Insuline-like growth factor type I selectively binds to G-quadruplex structures. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):31-38.
[2]. Fujimori J, et al. Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines. J Orthop Res. 2011 Nov;29(11):1707-11.

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