TMPyP4 tosylate (Synonyms: TMP-1363, TMPyP4 4-methylbenzenesulfonate) |
Catalog No.GC12092 |
TMPyP4 토실레이트(TMP 1363)는 G-사중체와 IGF-1 사이의 상호작용을 억제하는 사중체 특이적 리간드입니다. TMPyP4 토실레이트(TMP 1363)는 골육종 세포주에서 항종양 효과가 있는 텔로머라제 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 36951-72-1
Sample solution is provided at 25 µL, 10mM.
TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1[1]. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines[2].
References:
[1]. Chen H, et al. Insuline-like growth factor type I selectively binds to G-quadruplex structures. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):31-38.
[2]. Fujimori J, et al. Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines. J Orthop Res. 2011 Nov;29(11):1707-11.
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