Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Products for Metabolism
- Cat.No. Nombre del producto Información
- GC18575 2-hydroxy Tricosanoic Acid methyl ester 2-hydroxy Tricosanoic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in ripe and unripe strawberry homogenates, Pseudosuberites and S.
- GC49840 2-Methylbutyrylglycine A metabolite of isoleucine
- GC48617 2-Methylhexacosane An insect pheromone
- GC52170 2-Nitroamino-2-imidazoline
- GC42189 2-oxo Clopidogrel 2-oxo Clopidogrel is an intermediary metabolite of clopidogrel.
- GC12262 2-Phenyl-2-(1-piperidinyl)propane El 2-fenil-2-(1-piperidinil)propano es un inhibidor selectivo y reversible del CYP2B6 humano con una IC50 de 5,1 μM y una Ki de 5,6.
- GC42193 2-Thenoyltrifluoroacetone La 2-tenoiltrifluoroacetona es un agente quelante.
- GC52083 21-Deoxycortisone A corticosteroid metabolite of 11-keto progesterone
- GC40968 21-hydroxy Eplerenone 21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.
- GC18270 22(S)-hydroxy Cholesterol A synthetic oxysterol and LXR modulator
-
GC41614
24-dehydro Cholesterol
El 24-deshidrocolesterol es una molécula similar al colesterol.
- GC46243 24-dehydro Cholesterol-d6 An internal standard for the quantification of 24-dehydro cholesterol
- GC49365 25-Desacetyl Rifampicin A major active metabolite of rifampicin
- GC18490 2α-Mannobiose 2α-Mannobiose is a disaccharide composed of two mannose molecules linked by a 1-2 glycosidic bond.
- GC49658 3β-Cholic Acid A bile acid
- GC46068 3β-OH-7-Oxocholenic Acid A bile acid
- GC33059 3α-Aminocholestane 3α-Aminocholestano es un inhibidor selectivo de la inositol-5′-fosfatasa 1 (SHIP1) que contiene el dominio SH2 con una IC50 de ~2,5 μM.
- GC41480 3'-hydroxy Lidocaine 3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4.
- GC42312 3'-Sialyllactose (sodium salt) 3'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 3 position.
- GC52109 3,3′-Dipropylthiadicarbocyanine (iodide) 3,3′-La dipropiltiadicarbocianina (yoduro) es una sonda fluorescente que se utiliza a menudo como colorante trazador para evaluar el potencial de la membrana mitocondrial.
- GC46030 3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) An ENPP1 inhibitor
- GC42204 3,4,6-Tri-O-benzyl-β-D-Mannopyranose 1,2-(methyl orthoacetate) 3,4,6-Tri-O-benzyl-β-D-mannopyranose 1,2-(methyl orthoacetate) is a synthetic intermediate used in glycosylation reactions.
- GC12624 3,4-DAA synthetic derivative of the tryptophan metabolite anthranilic acid
- GC49427 3,5-Diiodo-L-thyronine La 3,5-diyodo-L-tironina es un metabolito endÓgeno.
- GC18205 3,5-Diiodothyroacetic Acid 3,5-Diiodothyroacetic acid (diac) is the acetic acid variant of thyroxine.
- GC49169 3,8’-Biapigenin 3,8’-Biapigenin es una biflavona en Hypericum perforatum L.
- GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate A metabolite of certain phenols and glycosides
- GC42198 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) An inactive metabolite of baclofen
- GC14282 3-acetyl-11-keto-β-Boswellic Acid El Ácido 3-acetil-11-ceto-β-boswélico (acetil-11-ceto-β-Ácido boswélico) es un compuesto triterpenoide activo del extracto de serrato de Boswellia y un nuevo activador Nrf2.
- GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide
- GC52129 3-Amino-5-hydroxybenzoic Acid
- GC10554 3-Cyano-7-ethoxycoumarin La 3-ciano-7-etoxicumarina es un sustrato fluorogénico del citocromo P-450 que genera un producto azul fluorescente tras la escisiÓn de la enzimaObjetivo: el citocromo P4503-ciano-7-etoxicumarina es una sonda fluorescente Útil en los estudios de dealquilasa microsomal.
- GC14713 3-Deazaadenosine 3-Deazaadenosina (clorhidrato) es un inhibidor de la S-adenosilhomocisteína hidrolasa, con un Ki de 3.
-
GC42261
3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors.
- GC49180 3-epi-25-hydroxy Vitamin D3 The C-3 epimer of 25-hydroxy vitamin D3
- GC18462 3-Formylsalicylic Acid 3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki = 120 nM), the enzyme that converts estrone sulfate to estrone.
- GC41632 3-hydroxy Carbofuran 3-hydroxy Carbofuran is an active metabolite of carbofuran, which is an insecticide that inhibits acetylcholinesterase in mammals and insects.
- GC42274 3-hydroxy Darifenacin 3-hydroxy Darifenacin is a metabolite of darifenacin.
- GC42275 3-hydroxy Desloratidine 3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.
- GC41565 3-hydroxy Medetomidine 3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine.
- GC42289 3-hydroxy Tridecanoic Acid methyl ester 3-hydroxy Tridecanoic acid methyl ester is a hydroxylated fatty acid methyl ester and major fatty acid component of A.
- GC42292 3-Hydroxypropionic Acid (sodium salt) 3-Hydroxypropionic acid is a building block in the synthesis of a variety of compounds with industrial applications, including acrylic acid, acrylamide, and 1,3-propanediol.
- GC48457 3-keto Fusidic Acid An active metabolite of fusidic acid
- GC49149 3-Methylglutaconic Acid A branched-chain organic acid
-
GC65595
3-Nitrocoumarin
El 3-Nitrocumarina (3-NC) es un inhibidor potente y selectivo de la Fosfolipasa C-gamma (PLC-gamma).
- GC17394 3-Nitropropionic acid El Ácido 3-nitropropiÓnico (β-Ácido nitropropiÓnico) es un inhibidor irreversible de la succinato deshidrogenasa.
- GC42307 3-O-methyl-L-DOPA (hydrate) 3-O-methyl-L-DOPA is a metabolite of L-DOPA, produced by the activity of catechol O-methyltransferase.
- GC42308 3-O-methyl-N-acetyl-D-Glucosamine La 3-O-metil-N-acetil-D-glucosamina es un potente inhibidor de la N-acetilglucosamina quinasa.
- GC60024 3-O-Methylquercetin La 3-O-metilquercetina (3-MQ), un constituyente principal de Rhamnus nakaharai, inhibe el cAMP total y el cGMP-fosfodiesterasa (PDE) de la trÁquea del conejillo de indias.
- GC40692 3-Propylxanthine La 3-propilxantina actÚa como antagonista selectivo y competitivo de los receptores A2B con Ki de 7 μM.
- GC12289 3-Thiatetradecanoic Acid activator of PPAR
-
GC52149
306-O12B
Un lípido catiónico ionizable.
- GC46678 4β-hydroxy Cholesterol-d7 An internal standard for the quantification of 4β-hydroxy cholesterol
- GC49367 4’-hydroxy Atomoxetine Glucuronide (hydrate) A metabolite of atomoxetine
- GC49252 4’-hydroxy Trazodone A metabolite of trazodone
- GC18527 4'-hydroxy Flurbiprofen A major active metabolite of flurbiprofen
- GC33071 4'-Methylchrysoeriol El 4'-metilcrisoeriol es un potente inhibidor de las enzimas del citocromo P450, con una IC50 de 19 nM para la EROD dependiente de P450 1B1 humana.
- GC41582 4(Z),7(Z)-Decadienoic Acid 4(Z),7(Z)-Decadienoic acid is a polyunsaturated fatty acid (PUFA).
- GC42326 4,6-O-Benzylidene-D-glucose 4,6-O-Benzylidene-D-glucose is a useful intermediate for the synthesis of carbohydrates.
- GC17159 4-(n-nonyl) Benzeneboronic Acid El Ácido 4-(n-nonil)bencenoborÓnico (compuesto 13) es un potente inhibidor dual FAAH y MAGL con valores IC50 de 9,1 nM y 7,9 μM, respectivamente.
- GC65517 4-(Trifluoromethyl)umbelliferone La 4-(trifluorometil)umbeliferona es un sustrato de sonda fluorescente para las enzimas del citocromo P450 hepÁtico de rata.
- GC49337 4-Acetamidobenzenesulfonamide A metabolite of asulam and sulfanilamide
- GC46069 4-Amino-5-(bromomethyl)-2-methylpyrimidine (hydrobromide) La 4-amino-5-(bromometil)-2-metilpirimidina (bromhidrato) es un posible inhibidor de la quinasa del receptor acoplado a proteÍna G (GRK).
- GC42337 4-Aminobenzoic Acid (sodium salt) 4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi.
- GC49494 4-Aminobenzylphosphonic Acid An alkaline phosphatase inhibitor
- GC18194 4-Epidoxycycline 4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline .
- GC18858 4-hydroxy Alternariol 4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol formed through cytochrome P450 (CYP450) metabolism.
- GC42405 4-hydroxy Atorvastatin (calcium salt) 4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
-
GC18425
4-hydroxy Atorvastatin lactone
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
- GC49575 4-hydroxy Omeprazole sulfide A metabolite of omeprazole
- GC40879 4-hydroxy Solifenacin N-oxide 4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin .
- GC42415 4-hydroxy Valsartan 4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan.
-
GC18417
4-hydroxy Xylazine
4-hidroxi Xilazina es un metabolito de la xilazina.
- GC60519 4-Hydroxyderricin La 4-hidroxiderricina, los principales ingredientes activos de Angelica keiskei Koidzumi, es un potente inhibidor selectivo de la MAO-B (inhibidores de la monoaminooxidasa) con una IC50 de 3,43 μM.
- GC42434 4-methyl-2-Oxovalerate (sodium salt) 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine.
- GC42445 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) El 4-metilumbeliferil β-D-galactopiranÓsido-6-sulfato (sal de sodio) es un tinte fluorescente.
- GC42446 4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside 4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside (4-μU-(GlcNAc)2) is a fluorogenic substrate for chitinases and chitobiosidases.
- GC42442 4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sodium salt) El 4-metilumbeliferil 2-sulfamino-2-desoxi-α-D-glucopiranÓsido (sal de sodio) es un sustrato fluorogénico de la heparina sulfamidasa, se desulfura en 4-MU-α-GlcNH2.
- GC40510 4-Methylumbelliferyl-α-D-Galactopyranoside El 4-metilumbeliferil-α-D-galactopiranÓsido (4MU-α-Gal), un sustrato para la α-galactosidasa A (GLA), es un sustrato azul profluorogénico.
- GC42449 4-Methylumbelliferyl-α-L-Iduronide (free acid) 4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate.
- GC49114 4-Methylumbelliferyl-β-D-Galactoside El 4-metilumbeliferil-β-D-galactosido es un sustrato fluorescente para la β-galactosidasa que, cuando se escinde, produce un fluorÓforo de cumarina fluorescente azul soluble en agua que se puede detectar con un fluoroenzimetro o fluorÓmetro.
-
GC42452
4-Methylumbelliferyl-β-D-N,N',N''-Triacetylchitotrioside
4-Metilumbeliferil-β-D-N,N',N''-triacetilquitotriosido es un sustrato fluorogénico para quitinasas y quitotriosidas.
- GC11870 4-Methylumbelliferyl-β-D-Glucopyranoside 4-Methylumbelliferyl-β-D-Glucopyranoside, un β-D-glucoside, es un sustrato fluorogénico para β-glucosidasa, se utiliza para analizar la actividad de β-glucosidasa.
- GC52117 4-Nitrophenyl α-D-Glucopyranoside A colorimetric α-glucosidase substrate
- GC42462 4-Nitrophenyl β-D-Cellotrioside 4-Nitrophenyl β-D-cellotrioside is a chromogenic substrate for endoglucanases and cellobiohydrolases.
- GC18209 4-Nitrophenyl β-D-Cellotetraoside 4-Nitrophenyl β-D-cellotetraoside is small molecule cellulose mimic that consists of a tetramer of D-glucose units joined by β-1-4-glycosidic bonds.
- GC42463 4-Nitrophenyl-N-acetyl-α-D-galactosaminide N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin.
- GC45841 4-Nitrophenyl-N-acetyl-β-D-glucosaminide A chromogenic substrate for N-acetyl-β-glucosaminidase
- GC35143 4-O-Methyl honokiol El 4-O-metil honokiol es un neolignano natural aislado de Magnolia officinalis, actÚa como un agonista de PPARγ e inhibe la actividad de NF-κB, utilizado para la investigaciÓn del cÁncer y la inflamaciÓn.
- GC49127 4-oxo Cyclophosphamide An inactive metabolite of cyclophosphamide
- GC41530 4-oxo Docosahexaenoic Acid 4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity.
- GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin
- GC11731 4-phenyl-1,2,3-Thiadiazole selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1)
- GC11758 4-phenyl-5-methyl-1,2,3-Thiadiazole CYP2B4 and CYP2E1 inhibitor
- GC10762 4β-hydroxy Cholesterol An endogenous marker for CYP3A4/5 activity
- GC48843 5α-Androst-16-en-3α-ol A pheromone with diverse biological activities
- GC49542 5α-Androstan-3β-ol A steroidal androgen
- GC49862 5α-Cholanic Acid-3,6-dione A secondary bile acid
- GC41399 5α-dihydro Levonorgestrel 5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel.
- GC40693 5α-hydroxy-6-keto Cholesterol 5α-hidroxi-6-ceto El colesterol es el principal metabolito de β-epÓxido (5α,6β-epoxicolesterol) durante la exposiciÓn directa de células epiteliales bronquiales humanas cultivadas intactas (16-HBE) al ozono.