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24-Norursodeoxycholic acid (nor-UDCA) (Synonyms: norUDCA, 24-Norursodeoxycholic Acid, Nourcholic Acid)

Katalog-Nr.GC33867

24-NorursodeoxycholsÄure (NorucholsÄure) ist ein seitenkettenverkÜrztes C23-Homolog von UDCA und hat starke anticholestatische, entzÜndungshemmende und antifibrotische Eigenschaften gezeigt.

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24-Norursodeoxycholic acid (nor-UDCA) Chemische Struktur

Cas No.: 99697-24-2

Größe Preis Lagerbestand Menge
1mg
29,00 $
Auf Lager
5mg
63,00 $
Auf Lager
10mg
99,00 $
Auf Lager
20mg
174,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestatic, anti-inflammatory and anti-fibrotic properties.

24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C23 homologue of UDCA and is previously shown to be highly effective in preclinical mouse models of cholestatic and fibrotic liver diseases. 24-norursodeoxycholic acid significantly reduces serum alkaline phosphatase (ALP) levels in a dose-dependent fashion. 24-norursodeoxycholic acid also significantly reduces γ-GT, ALT, and AST serum levels[1].

[1]. Fickert P, et al. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology. 2006 Feb;130(2):465-81.

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