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Andrastin A (Synonyms: NSC 697452)

Katalog-Nr.GC42806

Andrastin A is a meroterpenoid farnesyltransferase inhibitor.

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Andrastin A Chemische Struktur

Cas No.: 174232-42-9

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500μg
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Andrastin A is a meroterpenoid farnesyltransferase inhibitor. It increases the accumulation and effect of the chemotheraputic agent vincristine (sulfate) , most likely by binding to plasma membrane phosphoglycoprotein to prevent drug efflux. Andrastin A inhibits survival of Caco-2 cells with an IC50 of >50 μg/ml.

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