BPIQ-II (hydrochloride) (Synonyms: PD 158294) |
| Katalog-Nr.GC42968 |
BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 171179-37-6
Sample solution is provided at 25 µL, 10mM.
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BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM). It is selective for EGFR over an assortment of other tyrosine and serine/threonine kinases. Cellular studies indicate that BPIQ-II can enter cells and very selectively shut down EGF-stimulated signal transmission by binding competitively at the ATP site of EGFR.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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