E3 ligase Ligand 1A (Synonyms: VHL ligand 2; E3 ligase Ligand 1A) |
Katalog-Nr.GC33101 |
E3-Ligase-Ligand 1A (VHL-Ligand 2) ist der (S,R,S)-AHPC-basierte VHL-Ligand, der bei der Rekrutierung des von Hippel-Lindau (VHL)-Proteins verwendet wird. E3-Ligase-Ligand 1A kann verwendet werden, um ARV-771 zu synthetisieren, einen von Hippel-Landau (VHL) E3-Ligase-basierten BET PROTAC-Abbauer. ARV-771 baut das BET-Protein in kastrationsresistenten Prostatakrebszellen (CRPC) mit einem DC50 < 1 nM stark ab.
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Cas No.: 1948273-02-6
Sample solution is provided at 25 µL, 10mM.
E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer.
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