CAY10599 |
| Katalog-Nr.GC18876 |
Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1143573-33-4
Sample solution is provided at 25 µL, 10mM.
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Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. The prototypical compound for this class is the TZD rosiglitazone (BRL 49653), which is currently marketed for the treatment of diabetes. CAY10599 is a PPARγ agonist that is 4-fold more potent than rosiglitazone at the PPARγ receptor demonstrating an EC50 value of 0.05 uM. This compound shows high selectivity for PPARγ over PPARα (EC50 = 3.99 uM) or PPARδ (EC50 > 10 uM).
Review for CAY10599
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
Review for CAY10599
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