MT-3014 |
Katalog-Nr.GC36659 |
MT-3014 ist ein potenter, hochselektiver und in das Gehirn eindringender Phosphodiesterase 10A (PDE 10A)-Inhibitor mit IC50-Werten von 0,062 nM bzw. 0,09 nM fÜr humane PDE 10A bzw. bovine PDE 10A.
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Cas No.: 1332727-40-8
Sample solution is provided at 25 µL, 10mM.
MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively[1]. human PDE 10A|0.062 nM (IC50)|bovine PDE 10A|0.09 nM (IC50)
[1]. Koizumi Y, et al. Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety. Bioorg Med Chem. 2019 Jun 19.
Average Rating: 5
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