MT-3014 |
| Catalog No.GC36659 |
MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1332727-40-8
Sample solution is provided at 25 µL, 10mM.
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MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively[1]. human PDE 10A|0.062 nM (IC50)|bovine PDE 10A|0.09 nM (IC50)
[1]. Koizumi Y, et al. Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety. Bioorg Med Chem. 2019 Jun 19.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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