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Nanatinostat (Synonyms: CHR-3996)

Katalog-Nr.GC36691

Nanatinostat (CHR-3996) ist ein potenter, Klasse-I-selektiver und oral aktiver Inhibitor der Histon-Deacetylase (HDAC) mit einem IC50-Wert von 8 nM.

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Nanatinostat Chemische Struktur

Cas No.: 1256448-47-1

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Description Chemical Properties Product Documents Related Products

Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM[1]. IC50:8 nM ( HDAC)[1]

[1]. Moffat D, et al. Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor. J Med Chem. 2010 Dec 23;53(24):8663-78.

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