KDM5A-IN-1 |
| Katalog-Nr.GC32842 |
KDM5A-IN-1 ist ein potenter, oral bioverfÜgbarer Pan-Histon-Lysin-Demethylase-5 (KDM5)-Inhibitor mit IC50-Werten von 45 nM, 56 nM und 55 nM fÜr KDM5A, KDM5B bzw. KDM5C und mit einem EC50-Wert von 960 nM fÜr PC9 H3K4Me3. KDM5A-IN-1 ist deutlich weniger wirksam gegenÜber anderen KDM5B-Enzymen (1A, 2B, 3B, 4C, 6A, 7B).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1905481-36-8
Sample solution is provided at 25 µL, 10mM.
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KDM5A-IN-1 is an inhibitor histone demethylases. Target: Histone Demethylase
[1]. Kwong Wah LAI, et al. Pyrrolidine amide compounds as histone demethylase inhibitors. PCT Int. Appl. (2016), WO 2016057924 A1 20160414.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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