KHK-IN-1 hydrochloride (ketohexokinase inhibitor) |
| Katalog-Nr.GC30135 |
KHK-IN-1 Hydrochlorid (Ketohexokinase-Inhibitor) ist ein potenter Ketohexokinase (KHK)-Inhibitor mit einer IC50 von 12 nM. Er interagiert mit Asp-27B in der ATP-Bindungsregion von KHK.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1303470-48-5
Sample solution is provided at 25 µL, 10mM.
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KHK-IN-1 Hcl is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK.
[1]. Maryanoff BE, et al. Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5326-9. [2]. Maryanoff BE, et al. Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site. ACS Med Chem Lett. 2011 Apr 18;2(7):538-43.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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