Sphingolipids
Produkte für Sphingolipids
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GC45206
α-GalCer analog 8
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.
- GC45263 (+)-D-threo-PDMP (hydrochloride) (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP.
- GC45250 (-)-L-threo-PDMP (hydrochloride) (-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis.
- GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase.
- GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe.
- GC42050 1-β-D-Glucosylsphingadienine (d18:2 (4E,8E)) 1-β-D-Glucosylsphingadienin (d18:2 (4E,8E)) ist ein Glucosylsphingosin, das deacetylierte Lysolipidderivate von Glucosylcerebrosiden sind.
- GC42051 1-β-D-Glucosylsphingosine (d18:1) 1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides.
- GC18609 1-Deoxysphinganine (m18:0) 1-Desoxysphinganin (m18:0) (ES-285) ist eine antiproliferative (antitumorale) Verbindung marinen Ursprungs. 1-Desoxysphinganin (m18:0) hemmt das Wachstum der PC-3- und LNCaP-Zellen der Prostata durch intrazellulÄre Ceramid-Akkumulation und PKCζ Aktivierung.
- GC41544 1-Deoxysphingosine (m18:1(14Z)) 1-Deoxysphingosine (m18:1(14Z)) is an atypical sphingolipid that contains a double bond at the n-4 (14Z) native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.
- GC46050 1-Deoxysphingosine (m18:1(4E)) An atypical sphingolipid
- GC41907 13C C16 Sphingomyelin (d18:1/16:0) 13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion.
- GC41908 13C6 Glucosylsphingosine (d18:1) 13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS.
- GC42112 2-Acetyl-5-tetrahydroxybutyl Imidazole Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.
- GC42242 3'-sulfo Galactosylsphingosine (ammonium salt) 3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group.
- GC42295 3-keto Sphinganine (d12:0) (hydrochloride) 3-keto Sphinganine (d12:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).
- GC42297 3-keto Sphinganine (d6:0) (hydrochloride) 3-keto Sphinganine (d6:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).
- GC42298 3-keto Sphinganine (d8:0) (hydrochloride) 3-keto Sphinganine (d8:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).
- GC42369 4-Deoxypyridoxine (hydrochloride) 4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities.
- GC46765 A6770 A6770 ist ein oral aktiver, starker Sphingosin-1-Phosphat (S1P)-Lyase (S1PL)-Inhibitor.
- GC41406 AMP-Deoxynojirimycin The lipid messenger ceramide is converted to glucosylceramide by glucosylceramide synthase (GCS).
- GC42854 ARN14988 ARN14988 ist ein starker Inhibitor der sauren Ceramidase (ACDase) (IC50 = 12,8 nM fÜr das menschliche Enzym).
- GC42891 azido-FTY720 Azido-FTY720 ist ein photoaktivierbares Analogon von FTY720.
- GC42963 BODIPY-C12 Ceramide (d18:1/12:0) BODIPY-C12 Ceramide (B12Cer) is a fluorescently-tagged form of C12 ceramide that displays excitation/emission maxima of 505/540 nm, respectively.
- GC43003 C10 AV Ceramide (d18:1/10:0) AV-Ceramide is a fluorescently-tagged probe consisting of C-10 ceramide with an anthrylvinyl (AV) group attached to the end of the acyl chain.
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GC43004
C10 Ceramide (d18:1/10:0)
C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase.
- GC46974 C12 1-Deoxyceramide (m18:1/12:0) A medium-chain atypical ceramide
- GC43005 C12 3'-sulfo Galactosylceramide (d18:1/12:0) C12 3'-sulfo Galactosylceramide is a sulfated glycolipid, which are also known as sulfatides.
- GC43006 C12 Ceramide (d18:1/12:0) C12-Ceramid (d18:1/12:0) (N-Lauroyl-D-erythro-Sphingosin), ein natÜrlich vorkommendes Ceramid, wird durch Hydrolyse von C12-Sphingomyelin gebildet.
- GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid.
- GC43009 C12 NBD 3'-sulfo Galactosylceramide (d18:1/12:0) C12 NBD 3'-sulfo galactosylceramide is a sphingolipid that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group.
- GC43010 C12 NBD Ceramide (d18:1/12:0) C12 NBD Ceramid (d18:1/12:0) ist ein fluoreszierendes Analogon von Ceramid, es kann als Substrat in Ceramidase-Assays verwendet werden.
- GC43011 C12 NBD dihydro Ceramide (d18:0/12:0) C12 NBD dihydro Ceramide (d18:0/12:0) ist ein fluoreszierendes Ceramidase-Substrat.
- GC43012 C12 NBD Galactosylceramide (d18:1/6:0) C12-NBD-Galactosylceramid, fluoreszierender Farbstoff, ist ein biologisch aktives Derivat von Galactosylceramid, das mit einer fluoreszierenden C12-Nitrobenzoxadiazol (C12-NBD)-Gruppe markiert ist.
- GC43013 C12 NBD Globotriaosylceramide (C18:1/12:0) C12 NBD globotriaosylceramide is a biologically active derivative of globotriaosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD).
- GC43016 C12 NBD L-threo dihydro Ceramide (d18:0/12:0) C12 NBD L-threo dihydro Ceramide (d18:0/12:0) ist eine fluoreszierende Gruppe.
- GC43014 C12 NBD Lactosylceramide (d18:1/12:0) C12-NBD-Lactosylceramid (d18:1/12:0) ist ein Derivat von Lactosylceramid, das mit einer C12-NBD-Fluoreszenzgruppe markiert ist.
- GC43017 C12 NBD Phytoceramide (t18:0/12:0) C12 NBD phytoceramide is a biologically active derivative of phytosphingosine that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group.
- GC43018 C12 NBD Sphingomyelin (d18:1/12:0) C12 NBD sphingomyelin is a biologically active derivative of sphingomyelin that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group.
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GC43022
C14 Ceramide (d18:1/14:0)
C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6.
- GC43023 C15 Ceramide (d18:1/15:0) C15 Ceramide is a naturally occurring ceramide that has been found in L.
- GC43024 C15 Galactosylceramide (d18:1/15:0) C15 Galactosylceramide is a glycosphingolipid.
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GC43025
C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0)
C16 (2'(S)-hydroxy) Ceramide is the synthetic ceramide stereoisomer of N-(2'-(R)-hydroxypalmitoyl)-D-erythro-sphingosine.
- GC46975 C16 1-Deoxyceramide (m18:1/16:0) A long-chain atypical ceramide
- GC43026 C16 3'-sulfo Galactosylceramide (d18:1/16:0) C16 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
- GC43027 C16 Ceramide (d16:1/16:0) C16 Ceramide (d16:1/16:0) is a bioactive sphingolipid that induces ordered- and gel-phase formation and thermal stabilization of palmitoylsphingomyelin-rich domains in palmitoylphosphocholine (POPC) bilayers.
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GC43028
C16 Ceramide (d18:1/16:0)
Ceramide werden aus Sphingomyelin durch Aktivierung von Sphingomyelinase oder durch den de-novo-Syntheseweg generiert, der die koordinierte Wirkung von Serin-Palmitoyltransferase und Ceramidsynthase erfordert.
- GC43029 C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium salt) C16 Ceramide-1-phosphate (C16 C1P) is one of the main forms of C1P found in cells.
- GC46976 C16 Ceramide-d7 (d18:1-d7/16:0) An internal standard for the quantification of C-16 ceramide
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GC43030
C16 dihydro Ceramide (d18:0/16:0)
A bioactive sphingolipid
- GC43031 C16 Galactosylceramide (d18:1/16:0) C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid .
- GC43032 C16 Globotriaosylceramide (d18:1/16:0) C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide.
- GC43033 C16 Lactosylceramide (d18:1/16:0) C16 Lactosylceramide is an endogenous bioactive sphingolipid.
- GC43034 C16 Phytoceramide (t18:0/16:0) C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.
- GC43035 C16 Sphingomyelin (d18:1/16:0) Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid.
- GC43036 C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0) C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0) is a 2'-hydroxylated form of C16 dihydro ceramide .
- GC43037 C17 3'-sulfo Galactosylceramide (d18:1/17:0) C17 3'-sulfo Galactosylceramide is a synthetic sulfated glycolipid, which are also known as sulfatides.
- GC43038 C17 Ceramide (d18:1/17:0) C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine.
- GC43040 C17 dihydro Ceramide (d18:0/17:0) C17 dihydro Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine.
- GC43041 C17 Globotriaosylceramide (d18:1/17:0) C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
- GC43042 C17 Lactosylceramide (d18:1/17:0) C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
- GC43043 C17 Sphingomyelin (d18:1/17:0) C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
- GC43044 C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) (18:0 (2R/S-OH)-Ceramide) is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis.
- GC43045 C18 ((±)-2'-hydroxy) dihydro Ceramide (d18:0/18:0) C18 ((±)-2'-hydroxy) dihydro Ceramide (d18:0/18:0) is a 2'-hydroxylated form of C18 dihydro ceramide .
- GC43046 C18 3'-sulfo Galactosylceramide (d18:1/18:0) C18 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
- GC40140 C18 3'-sulfo Lactosylceramide (d18:1/18:0) C18 3'-sulfo Lactosylceramide (d18:1/18:0) is a sulfated glycosphingolipid.
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GC43047
C18 Ceramide (d18:1/18:0)
C18 Ceramide is an endogenous bioactive sphingolipid.
- GC46987 C18 Ceramide-d3 (d18:1/18:0-d3) An internal standard for the quantification of C18 ceramide
- GC46988 C18 Ceramide-d7 (d18:1-d7/18:0) An internal standard for the quantification of C18 ceramide
- GC48425 C18 D-threo Ceramide (d18:1/18:0) A synthetic ceramide
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GC43048
C18 dihydro Ceramide (d18:0/18:0)
A bioactive sphingolipid
- GC46990 C18 Galactosylceramide-d35 (d18:1/18:0-d35) An internal standard for the quantification of C18 galactosylceramide
- GC49806 C18 Ganglioside GD3-d3 (ammonium salt) An internal standard for the quantification of ganglioside GD3
- GC43049 C18 Globotriaosylceramide (d18:1/18:0) C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide.
- GC43050 C18 L-erythro Ceramide (d18:1/18:0) C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide.
- GC43051 C18 L-threo Ceramide (d18:1/18:0) C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids.
- GC43052 C18 Phytoceramide (t18:0/18:0) C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S.
- GC40141 C18 Phytoceramide-d3 (t18:0/18:0-d3) C18 Phytoceramide-d3 (t18:0/18:0-d3) is intended for use as an internal standard for the quantification of C18 phytoceramide (t18:0/18:0) by GC- or LC-MS.
- GC43053 C18 Sphingomyelin (d18:1/18:0) C18 Sphingomyelin is a naturally occurring form of sphingomyelin.
- GC43054 C18:1 3'-sulfo Galactosylceramide (d18:1/18:1(9Z)) C18:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
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GC43055
C18:1 Ceramide (d18:1/18:1(9Z))
C18:1 Ceramide is a naturally occurring ceramide.
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GC43057
C19 Ceramide (d18:1/19:0)
C19 Ceramide is a naturally occurring ceramide that has been found in J.
- GC43058 C2 3'-sulfo Galactosylceramide (d18:1/2:0) C2 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
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GC43059
C2 Adamantanyl Galactosylceramide (d18:1/2:0)
C2 Adamantanyl Galactosylceramide (d18:1/2:0) (AdaGalCer) is a bioactive sphingolipid.
- GC43060 C2 Adamantanyl Globotriaosylceramide (d18:1/2:0) C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain.
- GC43061 C2 Adamantanyl Glucosylceramide (d18:1/2:0) C2 Adamantanyl glucosylceramide (AdaGluCer) is a bioactive sphingolipid.
- GC43062 C2 Ceramide (d14:1/2:0) C2 Ceramide (d14:1/2:0) ist eine Zusammensetzung zur Diagnose von Krankheiten, die mit einer Überexpression von Cyclooxygenase 2 (COX2) verbunden sind. C2-Ceramid (d14:1/2:0) zeigt eine starke BindungsaktivitÄt an das COX2-Protein (aus dem Patent WO2019235824A1 entnommen).
- GC43063 C2 dihydro Ceramide (d18:0/2:0) C2 dihydro Ceramide is a metabolically inactive analog of C-2 ceramide.
- GC40708 C2 L-erythro Ceramide (d18:1/2:0) C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides.
- GC40709 C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43065 C2 Phytoceramide (t18:0/2:0) C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells.
- GC43066 C2 Sphingomyelin (d18:1/2:0) C2 Sphingomyelin is a synthetic cell-permeable derivative of sphingomyelin.
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GC43067
C20 Ceramide (d18:1/20:0)
Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway.
- GC43068 C20 Sphingomyelin (d18:1/20:0) C20 Sphingomyelin is a naturally occurring sphingolipid.
- GC45663 C22 1-Deoxyceramide (m18:1(14Z)/22:0) A long-chain atypical ceramide
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GC43069
C22 Ceramide (d18:1/22:0)
C-22 ceramide is an endogenous bioactive sphingolipid.
- GC46108 C22 dihydro 1-Deoxyceramide (m18:0/22:0) A very long-chain atypical ceramide
- GC46997 C22 Galactosylceramide (d18:1/22:0) A sphingolipid
- GC43070 C22 Glucosylceramide (d18:1/22:0) C22 Glucosylceramide (d18:1/22:0) is an endogenous glucosylceramide.
- GC47000 C22 Phytoceramide (t18:0/22:0) A sphingolipid
- GC47001 C22 Phytoceramide-d3 (t18:0/22:0-d3) An internal standard for the quantification of C22 phytoceramide