LSD1-IN-7 benzenesulfonate (Synonyms: CC-90011 benzenesulfonate; LSD1-IN-7 benzenesulfonate) |
| Katalog-Nr.GC39287 |
CC-90011 Benzolsulfonat ist ein potenter, selektiver, reversibler und oral aktiver Inhibitor der Lysin-spezifischen Demethylase-1 (LSD1) mit einem IC50 von 0,25 nM. CC-90011 Benzolsulfonat ist weniger enzymatische Hemmung gegen LSD2, MOA-A und MAO-B. CC-90011-Benzolsulfonat induziert die Zelldifferenzierung bei akuter myeloischer LeukÄmie (AML) und kleinzelligem Lungenkrebs (SCLC) und hat eine starke AntikrebsaktivitÄt.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2097523-60-7
Sample solution is provided at 25 µL, 10mM.
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LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity extracted from patent WO2017079670A1, compound 4-[2-(4-amino-piperidin-1-yl)-5-(3-fluoro-4-methoxy-phenyl)-1-methyl-6-oxo-1,6-dihydro-pyrimidin-4-yl]-2-fluorobenzonitrile[1].
[1]. Young K. Chen, et al. Compositions comprising an inhibitor of lysine specific demethylase-1. WO2017079670A1.
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