MB 0223 |
| Katalog-Nr.GC50574 |
Dynamin-related GTPase DRP1 partial inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2247732-89-2
Sample solution is provided at 25 µL, 10mM.
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Dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fusion.
Mallat et al (2018) Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1. Biochem.Biophys.Res.Commun. 499 556 PMID:29601815
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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