MOG (35-55) (mouse, rat) (trifluoroacetate salt) (Synonyms: MEVGWYRSPFSRVVHLYRNGK, Myelin Oligodendrocyte Glycoprotein (35-55)) |
Katalog-Nr.GC52419 |
An MOG antigen peptide
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Myelin oligodendrocyte glycoprotein (MOG) (35-55) is an antigen peptide of MOG, a protein involved in demyelinating CNS disorders.1,2 MOG (35-55) in combination with heat-killed M. tuberculosis and complete Freund's adjuvant (CFA) induces demyelination of the spinal cord, degeneration of the optic nerve, and visual impairments in mice.1 Immunization with MOG (35-55) in combination with adjuvants has been used to induce experimental autoimmune encephalomyelitis (EAE) in animal models of multiple sclerosis.1,2
1.Guo, X., Harada, C., Namekata, K., et al.Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient micePLoS One5(9)e13083(2010) 2.Zhang, F., Wei, W., Chai, H., et al.Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltrationJ. Immunol.190(3)1017-1025(2013)
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