Nebracetam hydrochloride (Synonyms: WEB 1881 FU hydrochloride) |
Katalog-Nr.GC38933 |
Nebracetamhydrochlorid, ein nootroper M1-Muscarin-Agonist, induziert einen Anstieg der intrazellulÄren Ca2+-Konzentration.
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Cas No.: 1177279-49-0
Sample solution is provided at 25 µL, 10mM.
Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i[1].
Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms[2]. Animal Model: Male Wistar rats weighing 200-250 g[2].
[1]. Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55(1):177-80. [2]. Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58(2):117-26.
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