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Nebracetam hydrochloride (Synonyms: WEB 1881 FU hydrochloride)

Catalog No.GC38933

Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration.

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Nebracetam hydrochloride Chemical Structure

Cas No.: 1177279-49-0

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2mg
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i[1].

Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms[2]. Animal Model: Male Wistar rats weighing 200-250 g[2].

[1]. Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55(1):177-80. [2]. Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58(2):117-26.

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