Pregnanediol-3-Glucuronide (Synonyms: Pregnanediol-3α-Glucuronide) |
| Katalog-Nr.GC41266 |
Pregnanediol-3-Glucuronid ist der wichtigste Endmetabolit von Progesteron und spielt eine wichtige Rolle bei physiologischen Prozessen wie dem weiblichen Menstruationszyklus, der Schwangerschaft (unterstützt die Schwangerschaft), der Embryogenese und der mütterlichen Immunantwort von Menschen und anderen Spezies.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1852-49-9
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Pregnanediol-3-glucuronide (PDG) is the primary urinary metabolite of the steroid hormone progesterone. [1] Levels of PDG in the urine correlate to levels of progesterone measured in the serum.[1] [2] Analysis of urinary PDG has been used to detect ovulatory and anovulatory menstrual cycles in women as well as to assess the fertility of ovulatory cycles.[3] [4]
Reference:
[1]. O'Connor, K.A., Brindle, E., Holman, D.J., et al. Urinary estrone conjugate and pregnanediol 3-glucuronide enzyme immunoassays for population research. Clin. Chem. 49(7), 1139-1148 (2003).
[2]. Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay. Clin. Chem. 37(6), 838-844 (1991).
[3]. Kassam, A., Overstreet, J.W., Snow-Harter, C., et al. Identification of anovulation and transient luteal function using a urinary pregnanediol-3-glucuronide ratio algorithm. Environ. Health Perspect. 104(4), 408-413 (1996).
[4]. Blackwell, L.F., Cooke, D.G., and Brown, S. The use of estrone-3-glucuronide and pregnanediol-3-Glucuronide Excretion Rates to Navigate the Continuum of Ovarian Activity. Front. Public Health 6:153, (2018).
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *