Sograzepide (Netazepide) (Synonyms: Netazepide; YF 476; YM-220) |
Katalog-Nr.GC31407 |
Sograzepide (Netazepide) (Netazepide; YF 476; YM-220) ist ein extrem potenter, hochselektiver und oral aktiver Gastrin/CCK-B-Antagonist mit einem IC50-Wert von 0,1 nM, hat eine hemmende Wirkung auf die Gastrin/CCK-A-AktivitÄt mit einem IC50 von 502 nM.
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Cas No.: 155488-25-8
Sample solution is provided at 25 µL, 10mM.
Sograzepide (Netazepide;YF476) is a gastrin/cholecystokinin 2 receptor (CCK2) antagonist.
[1]. Boyce M, et al. Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjects. Br J Clin Pharmacol. 2015 May;79(5):744-55.
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