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SPHINX31

Katalog-Nr.GC19456

SPHINX31 ist ein potenter und selektiver SRPK1-Inhibitor mit einem IC50 von 5,9 nM.

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SPHINX31 Chemische Struktur

Cas No.: 1818389-84-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].

References:
[1]. Batson J, et al. Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease. ACS Chem Biol. 2017 Mar 17;12(3):825-832.

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