Startseite>>Signaling Pathways>> PROTAC>> Ligand for Target Protein for PROTAC>>Target Protein-binding moiety 8

Target Protein-binding moiety 8 (Synonyms: N-Deshydroxyethyl BMS-354825)

Katalog-Nr.GC33350

Zielprotein-bindende Einheit 8 (N-Deshydroxyethyl BMS-354825) ist ein Metabolit von Dasatinib, Dasatinib ist ein Multi-Kinase-Inhibitor, der Bcr-Abl, die Src-Familie und Thrombozyten-Wachstumsfaktor-Rezeptorkinasen wirksam hemmt.

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Target Protein-binding moiety 8 Chemische Struktur

Cas No.: 910297-51-7

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Target Protein-binding moiety 8 is a compound binding to BCR-ABL, and used for inhibiting BCR-ABL activity.

Target Protein-binding moiety 8 (Compound 8) is a compound binding to BCR-ABL, and used for inhibiting BCR-ABL activity.

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

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