SMAP-2 (Synonyms: DT-1154) |
カタログ番号GC39440 |
SMAP-2 (DT-1154) は、経口で活性なプロテインホスファターゼ 2A (PP2A) 活性化剤で、抗がん作用があります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1809068-70-9
Sample solution is provided at 25 µL, 10mM.
SMAP-2 (DT-1154) is an orally bioavailable phosphatase 2A (PP2A) activator which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. SMAP-2 (DT-1154) inhibits the growth of KRAS-mutant lung cancers [1].
[1]. Sangodkar J, et al. Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. J Clin Invest. 2017 Jun 1;127(6):2081-2090.
Average Rating: 5
(Based on Reviews and 7 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *