α-Linolenic Acid ethyl ester-d5 (Synonyms: ALAEE-d5, Ethyl α-Linolenate-d5, Ethyl Linolenate-d5, LAEE-d5, Linolenic Acid ethyl ester-d5) |
| カタログ番号GC45601 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 203633-16-3
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
α-Linolenic acid ethyl ester-d5 is intended for use as an internal standard for the quantification of α-linolenic acid ethyl ester by GC- or LC-MS. α-Linolenic acid ethyl ester is an esterified form of α-linolenic acid . It increases cyclin E levels and the activity of Cdk2/cyclin E, ERK, and JNK in hepatic stellate cells when used at a concentration of 50 μM.1 α-Linolenic acid ethyl ester (25 μg/ml) inhibits the growth of S. mutans, C. albicans, and P. gingivalis by 98, 72, and 92%, respectively, in vitro.2 It has been found in biodiesel produced from castor oil using ethanol.3 α-Linolenic acid ethyl ester has been used as a substrate in lipid peroxidation assays for antioxidant activity.4
References
1. Li, J., Hu, W., Baldassare, J.J., et al. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci. 73(9), 1083-1096 (2003).
2. Huang, C.B., and Ebersole, J.L. A novel bioactivity of omega-3 polyunsaturated fatty acids and their ester derivatives. Mol. Oral Microbiol. 25(1), 75-80 (2010).
3. Concei••o, M.M., Fernandes, V.J., Jr., Bezerra, A.F., et al. Dynamic kinetic calculation of castor oil biodiesel. J. Therm. Anal. Calorim. 87(3), 865-869 (2007).
4. Miyake, T., and Shibamoto, T. Antioxidative activities of natural compounds found in plants. J. Agric. Food Chem. 45(5), 1819-1822 (1997).
| Cas No. | 203633-16-3 | SDF | |
| 同義語 | ALAEE-d5, Ethyl α-Linolenate-d5, Ethyl Linolenate-d5, LAEE-d5, Linolenic Acid ethyl ester-d5 | ||
| Canonical SMILES | [2H]C([2H])([2H])C([2H])([2H])/C=C\C/C=C\C/C=C\CCCCCCCC(OCC)=O | ||
| Formula | C20H29D5O2 | M.Wt | 311.5 |
| 溶解度 | Ethanol: soluble | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.2103 mL | 16.0514 mL | 32.1027 mL |
| 5 mM | 0.6421 mL | 3.2103 mL | 6.4205 mL |
| 10 mM | 0.321 mL | 1.6051 mL | 3.2103 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *