TAK-071 |
| カタログ番号GC31086 |
TAK-071 は、新規で強力かつ選択性の高いムスカリン性アセチルコリン受容体 1 (M1R) ポジティブ アロステリック モジュレーターです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1820812-16-5
Sample solution is provided at 25 µL, 10mM.
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TAK-071 is a novel muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1].
[1]. Sako Y, et al. TAK-071, a novel M1 positive allosteric modulator with low cooperativity, improves cognitive function in rodents with few cholinergic side effects. Neuropsychopharmacology. 2018 Aug 1. doi: 10.1038/s41386-018-0168-8.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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