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Terodiline hydrochloride

Catalog No.GC39186

테로딜린 염산염은 토끼 정관(M1), 심방(M2), 방광(M3) 및 회장 근육(M3)에서 각각 15, 160, 280 및 198nM의 Kbs를 갖는 M1 선택적 무스카린 수용체(mAChR) 길항제입니다. .

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Terodiline hydrochloride Chemical Structure

Cas No.: 7082-21-5

Size 가격 재고 수량
5mg
US$464.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Terodiline hydrochloride is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline hydrochloride also is a Ca2+ blocker. Terodiline hydrochloride acts as a treatment for urinary frequency and urge incontinence[1].

[1]. Noronha-Blob L, et al. (+/-)-Terodiline: an M1-selective muscarinic receptor antagonist. In vivo effects at muscarinic receptors mediating urinary bladder contraction, mydriasis and salivary secretion. Eur J Pharmacol. 1991 Aug 29;201(2-3):135-42.

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