Terodiline hydrochloride |
| カタログ番号GC39186 |
塩酸テロジリンは、ウサギの輸精管 (M1)、心房 (M2)、膀胱 (M3)、および回腸筋 (M3) における Kbs がそれぞれ 15、160、280、および 198 nM の M1 選択的ムスカリン受容体 (mAChR) 拮抗薬です。 .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7082-21-5
Sample solution is provided at 25 µL, 10mM.
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Terodiline hydrochloride is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline hydrochloride also is a Ca2+ blocker. Terodiline hydrochloride acts as a treatment for urinary frequency and urge incontinence[1].
[1]. Noronha-Blob L, et al. (+/-)-Terodiline: an M1-selective muscarinic receptor antagonist. In vivo effects at muscarinic receptors mediating urinary bladder contraction, mydriasis and salivary secretion. Eur J Pharmacol. 1991 Aug 29;201(2-3):135-42.
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