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Terodiline hydrochloride

Katalog-Nr.GC39186

Terodilinhydrochlorid ist ein M1-selektiver Muskarinrezeptor (mAChR)-Antagonist mit Kbs von 15, 160, 280 und 198 nM in Vas deferens (M1), VorhÖfen (M2), Blase (M3) bzw. Ileummuskel (M3) von Kaninchen .

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Terodiline hydrochloride Chemische Struktur

Cas No.: 7082-21-5

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Terodiline hydrochloride is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline hydrochloride also is a Ca2+ blocker. Terodiline hydrochloride acts as a treatment for urinary frequency and urge incontinence[1].

[1]. Noronha-Blob L, et al. (+/-)-Terodiline: an M1-selective muscarinic receptor antagonist. In vivo effects at muscarinic receptors mediating urinary bladder contraction, mydriasis and salivary secretion. Eur J Pharmacol. 1991 Aug 29;201(2-3):135-42.

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