Ferroptosis
Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.
Products Related to Ferroptosis(211)
- GC38429Dihydroartemisinic acidCAS: 85031-59-0Purity: >99.00%
El Ácido dihidroartemisÍnico (Ácido dihidroqinghao) es un precursor biosintético del agente antipalÚdico artemisinina.
- GC40211Ferrostatin-1 DiyneCAS: 2226204-90-4Purity: >98.00%
Ferrostatin-1 diyne is a ferroptosis inhibitor and analog of ferrostatin-1.
- GC40226Curcumin-d6CAS: 1335198-02-1Purity: >99.00%
La curcumina D6 (diferuloilmetano D6) es una curcumina marcada con deuterio (cÚrcuma amarilla).
- GC40228Fluvastatin-d6 (sodium salt)Purity: >95.00%
Fluvastatin-d6 is intended for use as an internal standard for the quantification of fluvastatin by GC- or LC-MS.
- GC41293Glutathione ethyl esterCAS: 92614-59-0Purity: >96.00%
Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides.
- GC420391-Stearoyl-2-15(S)-HETE-sn-glycero-3-PCCAS: 154436-51-8Purity: >98.00%
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC420401-Stearoyl-2-15(S)-HETE-sn-glycero-3-PECAS: 947381-58-0Purity: >98.00%
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC420411-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PCCAS: 154436-48-3Purity: >98.00%
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC420421-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PECAS: 154436-49-4Purity: >90.00%
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC43231Cerivastatin (sodium salt)CAS: 143201-11-0Purity: >98.00%
La cerivastatina (sal sÓdica) es un agente reductor de lÍpidos sintético y un inhibidor de la HMG-CoA reductasa muy potente, bien tolerado y activo por vÍa oral, con una Ki de 1,3 nM/L.
- GC43297Coenzyme Q2CAS: 606-06-4Purity: >95.00%
Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP.
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
La rosiglitazona (BRL 49653) potÁsica es un PPARγ selectivo activo por vÍa oral; agonista (EC50: 60 nM, Kd: 40 nM).
- GC44893Siramesine (fumarate)CAS: 163630-79-3Purity: >98.00%
Siramesine is an agonist of the sigma-2 (σ2) receptor (IC50 = 0.19 nM).
- GC45792Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)CAS: 39916-28-4Purity: >95.00%
An inducer of ferroptosis
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC38203 | WJ460 | 1415251-36-3 | >98.00% | |
WJ460 es un potente inhibidor de mioferlina (MYOF), que interactÚa directamente con MYOF y ejerce una actividad antimetastÁsica en el rango nanomolar en las células de cÁncer de mama. | ||||
| GC38429 | Dihydroartemisinic acid | 85031-59-0 | >99.00% | |
El Ácido dihidroartemisÍnico (Ácido dihidroqinghao) es un precursor biosintético del agente antipalÚdico artemisinina. | ||||
| GC40193 | UAMC-3203 | 2271358-64-4 | >98.00% | |
UAMC-3203 es un inhibidor de Ferroptosis potente y selectivo con un IC50 de 12 nM. | ||||
| GC40211 | Ferrostatin-1 Diyne | 2226204-90-4 | >98.00% | |
Ferrostatin-1 diyne is a ferroptosis inhibitor and analog of ferrostatin-1. | ||||
| GC40226 | Curcumin-d6 | 1335198-02-1 | >99.00% | |
La curcumina D6 (diferuloilmetano D6) es una curcumina marcada con deuterio (cÚrcuma amarilla). | ||||
| GC40228 | Fluvastatin-d6 (sodium salt) | - | >95.00% | |
Fluvastatin-d6 is intended for use as an internal standard for the quantification of fluvastatin by GC- or LC-MS. | ||||
| GC40922 | SRS11-92 | 1467047-25-1 | >98.00% | |
SRS11-92, un anÁlogo de Ferrostatin-1 (Fer-1), es un potente inhibidor de la ferroptosis. | ||||
| GC41293 | Glutathione ethyl ester | 92614-59-0 | >96.00% | |
Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. | ||||
| GC42039 | 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC | 154436-51-8 | >98.00% | |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. | ||||
| GC42040 | 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE | 947381-58-0 | >98.00% | |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. | ||||
| GC42041 | 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC | 154436-48-3 | >98.00% | |
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. | ||||
| GC42042 | 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE | 154436-49-4 | >90.00% | |
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. | ||||
| GC42928 | BHT | 128-37-0 | >99.00% | |
BHT es un antioxidante ampliamente utilizado en alimentos y en productos relacionados con alimentos. BHT es un inhibidor de Ferroptosis. | ||||
| GC43231 | Cerivastatin (sodium salt) | 143201-11-0 | >98.00% | |
La cerivastatina (sal sÓdica) es un agente reductor de lÍpidos sintético y un inhibidor de la HMG-CoA reductasa muy potente, bien tolerado y activo por vÍa oral, con una Ki de 1,3 nM/L. | ||||
| GC43297 | Coenzyme Q2 | 606-06-4 | >95.00% | |
Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. | ||||
| GC43329 | Cu-ATSM | 68341-09-3 | >95.00% | |
Cu-ATSM es un antioxidante que atrapa radicales (RTA) altamente potente e inhibidor de la peroxidación de (fosfolípidos), lo que explica su (su) capacidad para inhibir la ferroptosis. | ||||
| GC43623 | Erastin2 | 1695533-44-8 | >98.00% | |
Erastin2 es un potente inhibidor del sistema xc y agente inductor de ferroptosis. | ||||
| GC44214 | ML-162 | 1035072-16-2 | >99.50% | |
ML-162 es una molécula pequeña que inhibe Glutathione peroxidase 4 (GPX4), con un valor de IC 50 de 1.42μM | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
La rosiglitazona (BRL 49653) potÁsica es un PPARγ selectivo activo por vÍa oral; agonista (EC50: 60 nM, Kd: 40 nM). | ||||
| GC44893 | Siramesine (fumarate) | 163630-79-3 | >98.00% | |
Siramesine is an agonist of the sigma-2 (σ2) receptor (IC50 = 0.19 nM). | ||||
| GC44947 | SRS16-86 | 1793052-96-6 | >98.00% | |
El compuesto SRS16-86 pertenece a la tercera generación de inhibidores de la ferroptosis del grupo de las ferrostatinas. | ||||
| GC45248 | (-)-FINO2 | 869298-31-7 | >98.00% | |
(-)-FINO2 es un peróxido orgánico que puede inducir selectivamente la ferroptosis y se utiliza para estudiar los mecanismos de la ferroptosis y la terapia contra el cáncer | ||||
| GC45764 | Ciclopirox-d11 (sodium salt) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45792 | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) | 39916-28-4 | >95.00% | |
An inducer of ferroptosis | ||||