Ferroptosis
Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.
Products Related to Ferroptosis(211)
- GC38429Dihydroartemisinic acidCAS: 85031-59-0Purity: >99.00%
L'acide dihydroartémisinique (acide dihydroqinghao) est un précurseur biosynthétique de l'agent antipaludéen artémisinine.
- GC40211Ferrostatin-1 DiyneCAS: 2226204-90-4Purity: >98.00%
Ferrostatin-1 diyne is a ferroptosis inhibitor and analog of ferrostatin-1.
- GC40226Curcumin-d6CAS: 1335198-02-1Purity: >99.00%
La curcumine D6 (Diferuloylmethane D6) est une curcumine marquée au deutérium (jaune curcuma).
- GC40228Fluvastatin-d6 (sodium salt)Purity: >95.00%
Fluvastatin-d6 is intended for use as an internal standard for the quantification of fluvastatin by GC- or LC-MS.
- GC41293Glutathione ethyl esterCAS: 92614-59-0Purity: >96.00%
Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides.
- GC420391-Stearoyl-2-15(S)-HETE-sn-glycero-3-PCCAS: 154436-51-8Purity: >98.00%
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC420401-Stearoyl-2-15(S)-HETE-sn-glycero-3-PECAS: 947381-58-0Purity: >98.00%
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC420411-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PCCAS: 154436-48-3Purity: >98.00%
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC420421-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PECAS: 154436-49-4Purity: >90.00%
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC43231Cerivastatin (sodium salt)CAS: 143201-11-0Purity: >98.00%
La cérivastatine (sel de sodium) est un agent hypolipémiant synthétique et un inhibiteur de l'HMG-CoA réductase très puissant, bien toléré et actif par voie orale, avec un Ki de 1,3 nM/L.
- GC43297Coenzyme Q2CAS: 606-06-4Purity: >95.00%
Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP.
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
La rosiglitazone (BRL 49653) potassique est un PPARγ sélectif actif par voie orale; agoniste (EC50 : 60 nM, Kd : 40 nM).
- GC44893Siramesine (fumarate)CAS: 163630-79-3Purity: >98.00%
Siramesine is an agonist of the sigma-2 (σ2) receptor (IC50 = 0.19 nM).
- GC45792Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)CAS: 39916-28-4Purity: >95.00%
An inducer of ferroptosis
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC38203 | WJ460 | 1415251-36-3 | >98.00% | |
WJ460 est un inhibiteur puissant de myoferline (MYOF), ce qui interagit directement avec MYOE. WJ460 bloque l’invasion des cellules cancéreuses du sein que les valeurs d’IC 50 sont 43.37±3.42nM dans MDA-MB-231. | ||||
| GC38429 | Dihydroartemisinic acid | 85031-59-0 | >99.00% | |
L'acide dihydroartémisinique (acide dihydroqinghao) est un précurseur biosynthétique de l'agent antipaludéen artémisinine. | ||||
| GC40193 | UAMC-3203 | 2271358-64-4 | >98.00% | |
L'UAMC-3203 est un inhibiteur puissant et sélectif de la ferroptose avec une IC50 de 12 nM. | ||||
| GC40211 | Ferrostatin-1 Diyne | 2226204-90-4 | >98.00% | |
Ferrostatin-1 diyne is a ferroptosis inhibitor and analog of ferrostatin-1. | ||||
| GC40226 | Curcumin-d6 | 1335198-02-1 | >99.00% | |
La curcumine D6 (Diferuloylmethane D6) est une curcumine marquée au deutérium (jaune curcuma). | ||||
| GC40228 | Fluvastatin-d6 (sodium salt) | - | >95.00% | |
Fluvastatin-d6 is intended for use as an internal standard for the quantification of fluvastatin by GC- or LC-MS. | ||||
| GC40922 | SRS11-92 | 1467047-25-1 | >98.00% | |
Le SRS11-92, un analogue de la ferrostatine-1 (Fer-1), est un puissant inhibiteur de la ferroptose. | ||||
| GC41293 | Glutathione ethyl ester | 92614-59-0 | >96.00% | |
Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. | ||||
| GC42039 | 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC | 154436-51-8 | >98.00% | |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. | ||||
| GC42040 | 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE | 947381-58-0 | >98.00% | |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. | ||||
| GC42041 | 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC | 154436-48-3 | >98.00% | |
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. | ||||
| GC42042 | 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE | 154436-49-4 | >90.00% | |
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. | ||||
| GC42928 | BHT | 128-37-0 | >99.00% | |
Le BHT est un antioxydant largement utilisé dans les aliments et les produits alimentaires. Le BHT est un inhibiteur de la Ferroptose. | ||||
| GC43231 | Cerivastatin (sodium salt) | 143201-11-0 | >98.00% | |
La cérivastatine (sel de sodium) est un agent hypolipémiant synthétique et un inhibiteur de l'HMG-CoA réductase très puissant, bien toléré et actif par voie orale, avec un Ki de 1,3 nM/L. | ||||
| GC43297 | Coenzyme Q2 | 606-06-4 | >95.00% | |
Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. | ||||
| GC43329 | Cu-ATSM | 68341-09-3 | >95.00% | |
Cu-ATSM est un antioxydant piégeant les radicaux (RTA) très puissant et un inhibiteur de la peroxydation des (phospho)lipides, ce qui explique sa (leur) capacité à inhiber la ferroptose. | ||||
| GC43623 | Erastin2 | 1695533-44-8 | >98.00% | |
Erastin2 est un puissant inhibiteur du système xc- et un agent inducteur de ferroptose. | ||||
| GC44214 | ML-162 | 1035072-16-2 | >99.50% | |
ML-162 est une petite molécule qui inhibe la glutathion peroxydase 4 (GPX4), sa valeur d'IC50 est 1,42μM. | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
La rosiglitazone (BRL 49653) potassique est un PPARγ sélectif actif par voie orale; agoniste (EC50 : 60 nM, Kd : 40 nM). | ||||
| GC44893 | Siramesine (fumarate) | 163630-79-3 | >98.00% | |
Siramesine is an agonist of the sigma-2 (σ2) receptor (IC50 = 0.19 nM). | ||||
| GC44947 | SRS16-86 | 1793052-96-6 | >98.00% | |
SRS16-86 est un inhibiteur de la ferroptose de la classe ferrostatine de troisième génération. | ||||
| GC45248 | (-)-FINO2 | 869298-31-7 | >98.00% | |
(-)-FINO2 est un peroxyde organique qui peut induire sélectivement la ferroptose et qui est utilisé pour étudier les mécanismes de la ferroptose et les traitements anticancéreux. | ||||
| GC45764 | Ciclopirox-d11 (sodium salt) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45792 | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) | 39916-28-4 | >95.00% | |
An inducer of ferroptosis | ||||