DNQX (FG 9041) (Synonyms: 6,7Dinitroquinoxaline2,3dione, FG 9041) |
| Katalog-Nr.GC32755 |
DNQX (FG 9041) (FG 9041), ein Chinoxalinderivat, ist ein selektiver, potenter kompetitiver Nicht-NMDA-Glutamatrezeptorantagonist (IC50s = 0,5, 2 und 40 μ M fÜr AMPA-, Kainat- bzw. NMDA-Rezeptoren).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2379-57-9
Sample solution is provided at 25 µL, 10mM.
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DNQX (FG 9041) is a AMPA receptor antagonists.
DNQX (FG 9041), added 2 h after cell plating, induces a dose-dependent neurotoxicity.
[1]. Watkins JC et al. Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. Trends Pharmacol Sci. 1990 Jan;11(1):25-33. [2]. Honoré T et al. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science. 1988 Aug 5;241(4866):701-3.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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