DNQX (FG 9041) (Synonyms: 6,7Dinitroquinoxaline2,3dione, FG 9041) |
| カタログ番号GC32755 |
キノキサリン誘導体である DNQX (FG 9041) (FG 9041) は、選択的で強力な競合的非 NMDA グルタミン酸受容体アンタゴニストです (IC50 = 0.5、2 および 40 μ AMPA、カイネート、および NMDA 受容体に対してそれぞれ M)。
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Cas No.: 2379-57-9
Sample solution is provided at 25 µL, 10mM.
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DNQX (FG 9041) is a AMPA receptor antagonists.
DNQX (FG 9041), added 2 h after cell plating, induces a dose-dependent neurotoxicity.
[1]. Watkins JC et al. Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. Trends Pharmacol Sci. 1990 Jan;11(1):25-33. [2]. Honoré T et al. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science. 1988 Aug 5;241(4866):701-3.
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