SIS17 |
Katalog-Nr.GC37643 |
SIS17 ist ein Inhibitor der Histon-Deacetylase 11 (HDAC 11) von SÄugetieren mit einem IC50-Wert von 0,83 μM, der das Substrat der Demyristoylierung von HDAC11, die Serin-Hydroxymethyltransferase 2, hemmt, ohne andere HDACs zu hemmen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2374313-54-7
Sample solution is provided at 25 µL, 10mM.
SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM, inhibits the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs[1]. IC50: 0.83 μM (HDAC 11)[1]
[1]. Son SI, et al. Activity-Guided Design of HDAC11-Specific Inhibitors. ACS Chem Biol. 2019 Jul 19;14(7):1393-1397.
Average Rating: 5
(Based on Reviews and 29 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *