PROTAC ER Degrader-4 |
| Katalog-Nr.GC64350 |
PROTAC ER Degrader-4 ist ein von Hippel-Lindau-basierter PROATC-Östrogenrezeptor (ER)-Degrader, der mit einem IC50 von 0,8 nM an ER bindet. PROTAC ER Degrader-4 induziert den ER-Abbau in MCF-7-Zellen mit einem IC50 von 0,3 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2361114-15-8
Sample solution is provided at 25 µL, 10mM.
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PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].
PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM in the MCF-7 ER degradation cellular assay[1].
[1]. Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1.
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