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Startseite >> Signaling Pathways >> Immunology/Inflammation >> Innate Immunity

Innate Immunity

Produkte für  Innate Immunity

  1. Bestell-Nr. Artikelname Informationen
  2. GC43695 Folipastatin Folipastatin ist ein potenter Inhibitor der Phospholipase A2 mit einem IC50 von 39 μM. Folipastatin Chemical Structure
  3. GC43697 Formoterol O-β-D-Glucuronide Formoterol O-β-D-glucuronide is a metabolite of formoterol . Formoterol O-β-D-Glucuronide Chemical Structure
  4. GC52014 Forphenicinol An immunomodulator and a derivative of forphenicine Forphenicinol Chemical Structure
  5. GC40887 FTY720 (R)-Phosphate

    FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.

     FTY720 (R)-Phosphate Chemical Structure
  6. GC40008 Fuscin Fuscin, ein Pilzmetabolit, CCR5-Rezeptorantagonist mit Anti-HIV-Wirkung. Fuscin Chemical Structure
  7. GC47387 G6PDi-1 G6PDi-1 ist ein reversibler und nicht kompetitiver Glucose-6-Phosphat-Dehydrogenase (G6PD)-Inhibitor mit einem IC50von 0,07μM. G6PDi-1 Chemical Structure
  8. GC43727 Ganglioside GD1a mixture (sodium salt)

    Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.

     Ganglioside GD1a mixture (sodium salt) Chemical Structure
  9. GC52505 Ganglioside GT1b (bovine) (sodium salt) A sphingolipid Ganglioside GT1b (bovine) (sodium salt) Chemical Structure
  10. GC43735 Ganglioside GT1b Mixture (sodium salt)

    Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit.

     Ganglioside GT1b Mixture (sodium salt) Chemical Structure
  11. GC43736 Ganirelix (acetate) Ganirelix (Acetat) (Ganirest) ist ein injizierbarer kompetitiver Gonadotropin-Releasing-Hormon (GnRH)-Antagonist. Ganirelix (acetate) Chemical Structure
  12. GC49303 Ganoderic Acid DM GanoderinsÄure DM, ein natÜrliches Triterpenoid, isoliert aus Ganoderma lucidum, induziert DNA-SchÄden, G1-Zellzyklusarrest und Apoptose in menschlichen Brustkrebszellen. Ganoderic Acid DM Chemical Structure
  13. GC47400 GGTI 2133 (trifluoroacetate salt) A geranylgeranyl transferase I inhibitor GGTI 2133 (trifluoroacetate salt) Chemical Structure
  14. GC45706 GHK-Cu (acetate) A tripeptide-copper(II) complex GHK-Cu (acetate) Chemical Structure
  15. GC48744 Gliclazide-d4 An internal standard for the quantification of gliclazide Gliclazide-d4 Chemical Structure
  16. GC49437 Gliotoxin-13C13 An internal standard for the quantification of gliotoxin Gliotoxin-13C13 Chemical Structure
  17. GC43773 Glyburide (potassium salt) Glyburide is a sulfonylurea and an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.3 nM). Glyburide (potassium salt) Chemical Structure
  18. GC47406 Glyburide-d3 An internal standard for the quantification of glyburide Glyburide-d3 Chemical Structure
  19. GC43787 GSK106 (hydrochloride) GSK106 (Hydrochlorid) ist eine inaktive Kontrolle fÜr die selektiven PAD4-Inhibitoren GSK484 und GSK199. GSK106 (hydrochloride) Chemical Structure
  20. GC43788 GSK121 (trifluoroacetate salt) GSK-121 Trifluoracetate ein selektiver PAD4-Hemmer. GSK121 (trifluoroacetate salt) Chemical Structure
  21. GC43789 GSK199 (hydrochloride) GSK199 (Hydrochlorid) ist ein reversibler und selektiver PAD4-Inhibitor mit einer IC50 von 200 nM in Abwesenheit von Calcium. GSK199 (hydrochloride) Chemical Structure
  22. GC60183 GSK2245035 GSK2245035 ist ein hochwirksamer und selektiver intranasaler Agonist des Toll-Like-Rezeptors 7 (TLR7) mit bevorzugten Typ-1-Interferon (IFN)-stimulierenden Eigenschaften. GSK2245035 Chemical Structure
  23. GC48610 GSK3987 GSK3987 ist ein Pan-LXRα/β-Agonist mit EC50s von 50 nM, 40 nM fÜr LXRα-SRC1 bzw. LXRβ-SRC1. GSK3987 Chemical Structure
  24. GC47421 Hentriacontane An alkane with anti-inflammatory activity Hentriacontane Chemical Structure
  25. GC46154 Hexylglutathione An mtMGST1 inhibitor Hexylglutathione Chemical Structure
  26. GC47436 HT-2 Toxin-13C22 An internal standard for the quantification of HT-2 toxin HT-2 Toxin-13C22 Chemical Structure
  27. GC47448 Hydroxyzine-d8 (hydrochloride) Hydroxyzin-d8 (Dihydrochlorid) ist das mit Deuterium markierte Hydroxyzin-Dihydrochlorid. Hydroxyzine-d8 (hydrochloride) Chemical Structure
  28. GC43883 Hymeglusin Hymeglusin ist als Pilz-β-Lacton-Antibiotikum ein HMG-CoA-Synthase-Inhibitor (IC50 = 0,12 μM). Hymeglusin Chemical Structure
  29. GC52346 IDR 1002 (trifluoroacetate salt) A synthetic cationic innate defense regulator peptide IDR 1002 (trifluoroacetate salt) Chemical Structure
  30. GC43894 IKK2 Inhibitor VI

    Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling.

     IKK2 Inhibitor VI Chemical Structure
  31. GC47450 IL-4 Inhibitor IL-4-Inhibitor (Verbindung 52) ist ein IL-4-Inhibitor mit einem EC50 von 1,81 μM. IL-4 Inhibitor Chemical Structure
  32. GC45793 IM-93 IM-93 hemmt Ferroptose und NETosis mit einem IC50 von 0,45 μM fÜr die Hemmung des Zelltods. IM-93 Chemical Structure
  33. GC47454 IMS 2186 An anti-choroidal neovascularization agent IMS 2186 Chemical Structure
  34. GC52154 Inflammasome Inhibitor 4b Inflammasome Inhibitor 4b Chemical Structure
  35. GC48900 Isocurcumenol Isocurcumenol, ein aus Curcuma zedoaria Rhizomes isolierter Östrogenrezeptor alpha (ERα)-Inhibitor, besitzt AntitumoraktivitÄt mit IC50-Werten von 99,1 μg/ml bzw. 178,2 μg/ml in DLA- bzw. KB-Zellen. Isocurcumenol Chemical Structure
  36. GC49634 Isoflupredone Isoflupredon gehÖrt zur Klasse der Corticosteroide und entfaltet seine Wirkung durch Bindung an Glucocorticoid- und Mineralocorticoid-Rezeptoren von Tieren, wie z. B. Pferden. Isoflupredone Chemical Structure
  37. GC52027 Isolariciresinol Isolariciresinol ((+)-Cyclolariciresinol) kann zur Erforschung von Rheuma eingesetzt werden. Isolariciresinol Chemical Structure
  38. GC48715 ITH15004 A P2X7 receptor antagonist ITH15004 Chemical Structure
  39. GC52291 KAS 08 A STING activator KAS 08 Chemical Structure
  40. GC43996 KBC-007 KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). KBC-007 Chemical Structure
  41. GC44005 KIN1400 KIN1400 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. KIN1400 Chemical Structure
  42. GC44014 KT109 KT109 ist ein potenter und isoformselektiver Inhibitor der Diacylglycerollipase-β (DAGLβ) mit einem IC50 von 42 nM. KT109 Chemical Structure
  43. GC47533 L-778,123 A dual inhibitor of FTase and GGTase I L-778,123 Chemical Structure
  44. GC40770 L-erythro Sphingosine (d18:1) L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1). L-erythro Sphingosine (d18:1) Chemical Structure
  45. GC49560 L6H21 L6H21, ein Chalcone-Derivat, ist ein oral aktiver, potenter und spezifischer Inhibitor der myeloischen Differenzierung 2 (MD-2). L6H21 Chemical Structure
  46. GC44027 Lactosylsphingosine (d18:1) Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lactosylsphingosine (d18:1) Chemical Structure
  47. GC49471 LAMP1 Monoclonal Antibody (Clone Ly1C6) For immunochemical analysis of LAMP1 LAMP1 Monoclonal Antibody (Clone Ly1C6) Chemical Structure
  48. GC44035 LAS191859 LAS191859 is a potent antagonist of CRTH2/DP2 with IC50 values of 9.58, 14, 15.5, and 7.6 nM for recombinant human, rat, mouse, and guinea pig CRTH2/DP2 receptors, respectively. LAS191859 Chemical Structure
  49. GC52394 LC10 A lipidoid derivative of lithocholic acid LC10 Chemical Structure
  50. GC49751 Lefamulin Lefamulin (BC-3781) ist ein oral wirksames Antibiotikum. Lefamulin Chemical Structure
  51. GC47552 Leflunomide-d4 Leflunomid-d4 (HWA486-d4) ist das mit Deuterium bezeichnete Leflunomid. Leflunomid ist ein Pyrimidinsynthesehemmer, der die Dihydroorotatdehydrogenase (DHODH) hemmt und als krankheitsmodifizierendes Antirheumatikum wirkt. Leflunomide-d4 Chemical Structure
  52. GC18835 Leukotriene A4 methyl ester Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. Leukotriene A4 methyl ester Chemical Structure
  53. GC40278 Leukotriene B3 LTB3 is the LTA hydrolase metabolite of LTA3 in the leukotriene biosynthetic pathway. Leukotriene B3 Chemical Structure
  54. GC44052 Leukotriene B4 dimethyl amide LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. Leukotriene B4 dimethyl amide Chemical Structure
  55. GC47556 Leukotriene B4-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Leukotriene B4-d4 Chemical Structure
  56. GC49597 Leukotriene B4-d5 An internal standard for the quantification of LTB4 Leukotriene B4-d5 Chemical Structure
  57. GC41107 Leukotriene B5 Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities. Leukotriene B5 Chemical Structure
  58. GC44054 Leukotriene C4 methyl ester Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. Leukotriene C4 methyl ester Chemical Structure
  59. GC49020 Levomefolate-13C-d3 An internal standard for the quantification of levomefolate Levomefolate-13C-d3 Chemical Structure
  60. GC41517 Linoleic Acid ethyl ester LinolsÄureethylester hemmen die Entwicklung atherosklerotischer LÄsionen und die Expression von EntzÜndungsmediatoren. Linoleic Acid ethyl ester Chemical Structure
  61. GC41363 Linoleoyl Phenylalanine N-Linoleoyl phenylalanine is an endogenous N-acyl amine found in D. Linoleoyl Phenylalanine Chemical Structure
  62. GC18552 Lipoxin A4

    Eine Trihydroxy-Fettsäure mit einem konjugierten Tetraen.

     Lipoxin A4 Chemical Structure
  63. GC18680 Lipoxin A4 methyl ester

    Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4.

     Lipoxin A4 methyl ester Chemical Structure
  64. GC40609 Lipoxin A5 Lipoxin A5 (LXA5) is produced by enzymatic transformation of EPA by leukocytes. Lipoxin A5 Chemical Structure
  65. GC18681 Lipoxin B4 Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes. Lipoxin B4 Chemical Structure
  66. GC41169 Lipoxin B4 methyl ester Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4. Lipoxin B4 methyl ester Chemical Structure
  67. GC47570 Lipoxygenin An inhibitor of 5-LO Lipoxygenin Chemical Structure
  68. GC44078 LL-37 amide (trifluoroacetate salt) LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. LL-37 amide (trifluoroacetate salt) Chemical Structure
  69. GC52074 Loratadine N-oxide Loratadin-n-oxid ist ein Metabolit von Loratadin. Loratadine N-oxide Chemical Structure
  70. GC47575 Loratadine-d5 An internal standard for the quantification of loratadine Loratadine-d5 Chemical Structure
  71. GC48639 Lornoxicam-d4 An internal standard for the quantification of lornoxicam Lornoxicam-d4 Chemical Structure
  72. GC44093 Lutein Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina. Lutein Chemical Structure
  73. GC44101 Lyso-Globotriaosylceramide (d18:1) Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. Lyso-Globotriaosylceramide (d18:1) Chemical Structure
  74. GC40980 Maresin 2 Maresin 2 ist ein entzÜndungshemmender und auflÖsungsfÖrdernder Mediator aus menschlichen Makrophagen. Maresin 2 Chemical Structure
  75. GC41595 Matairesinol Matairesinol verleiht einem allergischen Dermatitis-Mausmodell antiallergische Wirkungen. Matairesinol Chemical Structure
  76. GC44138 MCTR1 Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. MCTR1 Chemical Structure
  77. GC44139 MCTR2 Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. MCTR2 Chemical Structure
  78. GC44140 MCTR3 Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. MCTR3 Chemical Structure
  79. GC44156 MeOSuc-AAPV-pNA MeOSuc-AAPV-pNA ist ein empfindliches fluorogenes Substrat von menschlicher Leukozyten- und Schweine-Pankreas-Elastase. MeOSuc-AAPV-pNA Chemical Structure
  80. GC44157 MeOSuc-Ala-Ala-Pro-Val-AMC MeOSuc-Ala-Ala-Pro-Val-AMC ist ein fluorogenes Substrat fÜr humane Leukozyten- und Schweine-Pankreas-Elastase (Km: 362 μ M, Ex = 380 nm, Em = 460 nm). MeOSuc-Ala-Ala-Pro-Val-AMC Chemical Structure
  81. GC48907 Metaxalone-d6 An internal standard for the quantification of metaxalone Metaxalone-d6 Chemical Structure
  82. GC44212 MK-886 (sodium salt) Arachidonic acid and selected other polyunsaturated fatty acids are stereoselectively oxygenated at carbon 5 by the non-heme iron containing enzyme 5-lipoxygenase (5-LO). MK-886 (sodium salt) Chemical Structure
  83. GC44237 MMP-9 Inhibitor I MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). MMP-9 Inhibitor I Chemical Structure
  84. GC18612 MMP-9/MMP-13 Inhibitor I MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both). MMP-9/MMP-13 Inhibitor I Chemical Structure
  85. GC47698 Mometasone Mometason ist ein inhalatives Glucocorticoid. Mometasone Chemical Structure
  86. GC49903 MRT67307 (hydrochloride) A kinase inhibitor MRT67307 (hydrochloride) Chemical Structure
  87. GC48335 N-glycolyl-Ganglioside GM3 Mixture (ammonium salt) A mixture of N-glycolyl-ganglioside GM3 N-glycolyl-Ganglioside GM3 Mixture (ammonium salt) Chemical Structure
  88. GC40081 Nargenicin

    Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S.

     Nargenicin Chemical Structure
  89. GC49681 Necrosulfonamide-d4 Necrosulfonamid-d4 ist das mit Deuterium markierte Necrosulfonamid. Necrosulfonamid ist ein Nekroptose-Hemmer, der selektiv auf das Kinase-DomÄnen-Ähnliche Protein (MLKL) der gemischten Abstammungslinie abzielt. Necrosulfonamid verhindert, dass der MLKL-RIP1-RIP3-Nekrosomenkomplex mit seinen nachgeschalteten Effektoren interagiert. MLKL ist ein entscheidendes Substrat von RIP3 wÄhrend der Nekroseinduktion. Necrosulfonamide-d4 Chemical Structure
  90. GC44376 Neuromedin N (trifluoroacetate salt) Neuromedin N is a neurotensin-like hexapeptide that is synthesized from the same precursor as neurotensin. Neuromedin N (trifluoroacetate salt) Chemical Structure
  91. GC44388 NF-κB Control NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. NF-κB Control Chemical Structure
  92. GC48985 NF-κB Inhibitor (trifluoroacetate salt) A cell-permeable peptide that blocks nuclear import of NF-κB NF-κB Inhibitor (trifluoroacetate salt) Chemical Structure
  93. GC52384 NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) A cell-permeable form of NFAT inhibitor NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) Chemical Structure
  94. GC49186 O-Demethyl Apremilast An active metabolite of apremilast O-Demethyl Apremilast Chemical Structure
  95. GC45536 Oleic Acid-13C   Oleic Acid-13C Chemical Structure
  96. GC52318 Oleic Acid-13C5 An internal standard for the quantification of oleic acid Oleic Acid-13C5 Chemical Structure
  97. GC47818 Oleic Acid-d17 An internal standard for the quantification of oleic acid Oleic Acid-d17 Chemical Structure
  98. GC49457 Oleoyl-Coenzyme A (sodium salt)

    An acyl-CoA thioester

     Oleoyl-Coenzyme A (sodium salt) Chemical Structure
  99. GC49815 Oleuropein aglycone A polyphenol with diverse biological activities Oleuropein aglycone Chemical Structure
  100. GC44505 Oleyl Anilide AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl Anilide Chemical Structure
  101. GC48405 Osanetant (hydrate) An NK3 receptor antagonist Osanetant (hydrate) Chemical Structure

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