Serine Protease
Serine proteases, named for the nucleophilic Ser residue at the active site, are a large and diverse group of proteases (accounting for approximately one-third of all proteases) that are characterized by the presence of the Asp-His-Ser “charge relay” system (catalytic triad) in their chemical structures. However, with the development of technology, a variety of novel serine proteases with catalytic triads and dyads have been discovered, including Ser-His-Glu, Ser-Lys/His, His-Ser-His and N-terminal Ser. Serine proteases are traditionally divided into four clans based on the Asp-His-Ser triad in different structural contexts, including chymotrypsin-like proteases, subtilisin-like proteases, carboxypeptidase Y-like proteases and Clp protease-like proteases.
Produkte für Serine Protease
- Bestell-Nr. Artikelname Informationen
-
GC14502
AEBSF.HCl
AEBSF.HCl is a broad-spectrum irreversible inhibitor of serine proteases, which can inhibit chymotrypsin, kallikrein, plasmin, thrombin, trypsin and related thrombolytic enzymes.
-
GC12900
Aprotinin
Ein Serinprotease-Inhibitor
- GC15682 Chymostatin Chymostatin ist ein potenter Cathepsin-G-Inhibitor.
-
GC10027
Leupeptin, Microbial
Ein reversibler Protease-Inhibitor
- GC10613 Nafamostat Mesylate(FUT-175) A serine protease inhibitor
-
GC10477
PMSF
Ein unspezifischer, irreversibler Serinprotease-Inhibitor.
- GC17711 PPACKII (trifluoroacetate salt) glandular and plasma kallikreins inhibitor
- GC49221 QLT0267 An ILK inhibitor
- GC13967 Tosyllysine Chloromethyl Ketone (hydrochloride) N-alpha-Tosyl-L-Lysin-Chloromethylketon (TLCK), ein Trypsin-Ähnlicher Protease-Inhibitor, sensibilisiert HeLa-Zellen fÜr Fas-vermittelten Zelltod.
- GC13421 UCF 101 UCF 101 ist ein selektiver und kompetitiver Inhibitor der pro-apoptotischen Protease Omi/HtrA2 mit einem IC50-Wert von 9,5 μM für His-Omi.
- GC26017 UK-371804 HCl UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).