bpV(pic) (potassium hydrate) (Synonyms: Bisperoxovanadium(pic)) |
| カタログ番号GC18718 |
bpV（pic）は、複数の異なるタンパク質チロシンホスファターゼ（PTP）を阻害するビスペルオキソバナジウム（bpV）化合物であり、PTENに対して選択的です（IC50 = 31 nM）。
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Cas No.: 148556-27-8
Sample solution is provided at 25 µL, 10mM.
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bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 12.7 μM), and PTP-1βB (IC50 = 61 μM). bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes.
Review for bpV(pic) (potassium hydrate)
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